The prevalence and clinical characteristics of esophageal involvement in patients with Behçet's disease: a single center experience in Korea.

The prevalence and clinical characteristics of esophageal involvement in patients with Behçet's disease: a single center experience in Korea.
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DOI:
10.3346/jkms.2009.24.1.52
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发表时间:
2009-02
影响因子:
4.5
通讯作者:
Kim WH
Kim WH
中科院分区:
医学4区
文献类型:
--
作者:
Yi SW;Cheon JH;Kim JH;Lee SK;Kim TI;Lee YC;Kim WH

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虽然已经报道了大量关于白塞氏病 (BD) 肠道受累的临床信息,但 BD 食管受累尚未得到广泛研究。本研究的目的是评估 BD 食管受累的患病率及其临床特征。我们回顾性回顾了 1990 年 1 月至 2006 年 6 月期间在韩国一家三级机构诊断为 BD 的 842 名患者的医疗记录。在 842 名 BD 患者中,129 名患者 (15.3%) 出现上消化道症状,需要通过食管胃十二指肠镜检查进行检查。 129 名患者中有 6 名(4.7%)发现食管受累。白塞氏病的活动指数在有或没有食管受累的患者中没有差异。所有食管受累的患者对药物治疗反应良好,没有一人出现严重并发症。我们的研究结果表明,BD 食管受累的患病率非常低,大多数受累患者很少出现并发症,并且对药物治疗反应良好。
While a significant amount of clinical information has been reported concerning intestinal involvement in Behçet's disease (BD), esophageal involvement in BD has not yet been studied extensively. The aim of this study was to evaluate the prevalence of esophageal involvement in BD and its clinical characteristics. We retrospectively reviewed the medical records of 842 patients diagnosed with BD at a single tertiary institution in Korea between January 1990 and June 2006. Of the 842 patients with BD, 129 patients (15.3%) experienced upper gastrointestinal symptoms that required inspection through esophagogastroduodenoscopy. Esophageal involvement was found in 6 (4.7%) of the 129 patients. The activity index of Behçet's disease did not differ among patients with or without esophageal involvement. All patients with esophageal involvement responded well to medical treatment and no one experienced serious complications. The results of our study demonstrate that the prevalence of esophageal involvement in BD is very low and that most patients with such involvement face few complications and respond well to medical treatment.
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