Associations of vitamin D intake with 25-hydroxyvitamin D in overweight and racially/ethnically diverse US children.
Associations of vitamin D intake with 25-hydroxyvitamin D in overweight and racially/ethnically diverse US children.
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DOI：
10.1016/j.jand.2013.05.025
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发表时间：
2013-11
影响因子：
4.8
通讯作者：
Sacheck, Jennifer M.
中科院分区：
文献类型：
--
作者：
Au, Lauren E.;Rogers, Gail T.;Harris, Susan S.;Dwyer, Johanna T.;Jacques, Paul F.;Sacheck, Jennifer M.
超重儿童和少数族裔面临维生素 D 缺乏的风险。关于不符合膳食维生素 D 建议的超重儿童和少数民族是否面临 25 羟基维生素 D (25OHD) 水平低的风险，目前的信息很少。作为 2005-2006 年国家健康和营养检查调查的一部分，对 3,310 名儿童/青少年从食品和膳食补充剂中摄入的维生素 D 进行了估计。体重状况分为健康体重或超重/肥胖。家长报告的种族/民族被分类为非西班牙裔白人、非西班牙裔黑人、墨西哥裔美国人或其他。调整后的逻辑回归用于确定未达到估计平均要求 (EAR) 的儿童 25OHD 不足的风险是否增加。近 75% 的儿童未能达到 EAR 要求。总体而言，未达到 EAR 与 25OHD 不足相关（比值比 = 2.5；95% CI 1.4 至 4.5）。然而，这种关联因体重状况（P=0.02）和种族/民族（P=0.02）而异。未达到 EAR 的超重/肥胖儿童发生 25OHD 不足的风险是达到 EAR 的超重/肥胖儿童的五倍（95% CI 2.0 至 12.7；P<0.001）。摄入量低于 EAR 的非西班牙裔黑人患 25OHD 不足的风险比达到 EAR 的非西班牙裔黑人高出近四倍（95% CI 1.5 至 9.7；P<0.01）。大多数美国儿童未能达到当前的维生素 D 推荐标准。超重/肥胖和非西班牙裔黑人儿童在不食用 EAR 时尤其可能面临 25OHD 不足的风险。
Overweight children and minorities are at risk of vitamin D deficiency. Little information exists on whether overweight children and minorities who do not meet dietary vitamin D recommendations are at risk for low 25-hydroxyvitamin D (25OHD) status. Vitamin D intake from foods and dietary supplements was estimated in 3,310 children/adolescents who were examined as part of the 2005-2006 National Health and Nutrition Examination Survey. Weight status was dichotomized into healthy weight or overweight/obese. Parent-reported race/ethnicity was categorized as non-Hispanic white, non-Hispanic black, Mexican American, or other. Adjusted logistic regression was used to determine whether children who did not achieve the Estimated Average Requirement (EAR) were at increased risk for inadequate 25OHD. Nearly 75% of children failed to meet the EAR. Overall, not meeting the EAR was associated with inadequate 25OHD (odds ratio=2.5; 95% CI 1.4 to 4.5). However, this association differed by weight status (P=0.02) and race/ethnicity (P=0.02). Overweight/obese children who failed to meet the EAR were five times more likely to be at risk for inadequate 25OHD than overweight/obese children who met it (95% CI 2.0 to 12.7; P<0.001). Non-Hispanic blacks with intakes below the EAR were nearly four times more likely to be at risk for inadequate 25OHD than those who met the EAR (95% CI 1.5 to 9.7; P<0.01). The majority of US children failed to meet current vitamin D recommendations. Overweight/obese and non-Hispanic black children were especially likely to be at risk for inadequate 25OHD when not consuming the EAR.
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