The "Great Obstetrical Syndromes" are associated with disorders of deep placentation.

The "Great Obstetrical Syndromes" are associated with disorders of deep placentation.
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DOI:
10.1016/j.ajog.2010.08.009
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发表时间:
2011-03
影响因子:
9.8
通讯作者:
Romero R
Romero R
中科院分区:
医学1区
文献类型:
--
作者:
Brosens I;Pijnenborg R;Vercruysse L;Romero R

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深度胎盘缺陷与一系列妊娠并发症有关,包括先兆子痫、宫内生长受限、早产、胎膜早破、晚期自然流产和胎盘早剥。支持这些并发症的胎盘血管床疾病通常通过有针对性的活组织检查来调查。在这篇综述中,我们对活检技术进行了评价,以总结深部胎盘缺陷的显著类型,并根据螺旋动脉肌层段的限制程度和梗阻性病变将深部胎盘缺陷分为3种类型。
Defective deep placentation has been associated with a spectrum of complications of pregnancy including preeclampsia, intrauterine growth restriction, preterm labor, preterm premature rupture of membranes, late spontaneous abortion and abruption placentae. The disease of the placental vascular bed that underpins these complications is commonly investigated with targeted biopsies. In this review, we critically evaluate the biopsy technique to summarize the salient types of defective deep placentation and propose criteria for the classification of defective deep placentation into 3 types based on the degree of restriction of remodelling and the presence of obstructive lesions in the myometrial segment of the spiral arteries.
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