Ferritin for the clinician.
Ferritin for the clinician.
复制标题
供临床医生使用的铁蛋白。
DOI:
10.1016/j.blre.2008.08.001
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发表时间:
2009-05
期刊:
影响因子:
7.4
通讯作者:
Torti, Frank M.
中科院分区:
文献类型:
--
作者:
Knovich, Mary Ann;Storey, Jonathan A.;Coffman, Lan G.;Torti, Suzy V.;Torti, Frank M.
Ferritin, a major iron storage protein, is essential to iron homeostasis and is involved in a wide range of physiologic and pathologic processes. In clinical medicine, ferritin is predominantly utilized as a serum marker of total body iron stores. In cases of iron deficiency and overload, serum ferritin serves a critical role in both diagnosis and management. Elevated serum and tissue ferritin are linked to coronary artery disease, malignancy, and poor outcomes following stem cell transplantation. Ferritin is directly implicated in less common but potentially devastating human diseases including sideroblastic anemias, neurodegenerative disorders, and hemophagocytic syndrome. Additionally, recent research describes novel functions of ferritin independent of iron storage.
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影响因子:
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