Physical and Chemical Factors Influencing the Printability of Hydrogel-based Extrusion Bioinks.
Physical and Chemical Factors Influencing the Printability of Hydrogel-based Extrusion Bioinks.
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影响水凝胶挤出生物油墨印刷适性的物理和化学因素。
DOI：
10.1021/acs.chemrev.0c00015
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发表时间：
2020-10-14
期刊：
影响因子：
62.1
通讯作者：
Lee SJ
中科院分区：
文献类型：
--
作者：
Lee SC;Gillispie G;Prim P;Lee SJ
生物打印研究人员一致认为，“可打印性”是生物墨水发展的一个关键特征，但这个术语的含义和实验测量它的最佳方法都还没有确定。此外，人们对决定生物墨水可印刷性的潜在机制知之甚少。透彻理解这些机制是有意设计新型生物墨水的关键。为了本综述的目的，可印刷性领域被定义为生物打印所特有的、在打印过程中发生的生物墨水要求。在这个领域内，印刷性的不同方面和影响它们的因素进行了审查。生物墨水的可压缩性、长丝分类、形状保真度和打印精度，详细检查了它们的流变性能、化学结构和打印参数。讨论了这些关系，并确定了需要进一步研究的领域。这篇综述旨在帮助生物链接的发展过程，它将继续在生物打印、组织工程和再生医学的成功与失败中发挥重要作用。
Bioprinting researchers agree that “printability” is a key characteristic for bioink development, but neither the meaning of the term nor the best way to experimentally measure it has been established. Furthermore, little is known with respect to the underlying mechanisms which determine a bioink’s printability. A thorough understanding of these mechanisms is key to the intentional design of new bioinks. For the purposes of this review, the domain of printability is defined as the bioink requirements which are unique to bioprinting and occur during the printing process. Within this domain, the different aspects of printability and the factors which influence them are reviewed. The extrudability, filament classification, shape fidelity, and printing accuracy of bioinks are examined in detail with respect to their rheological properties, chemical structure, and printing parameters. These relationships are discussed and areas where further research is needed, are identified. This review serves to aid the bioink development process, which will continue to play a major role in the successes and failures of bioprinting, tissue engineering, and regenerative medicine going forward.
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影响因子：
9
作者：
Athirasala A;Tahayeri A;Thrivikraman G;França CM;Monteiro N;Tran V;Ferracane J;Bertassoni LE
通讯作者：
Bertassoni LE
影响因子：
16.6
作者：
Appel EA;Tibbitt MW;Webber MJ;Mattix BA;Veiseh O;Langer R
通讯作者：
Langer R
影响因子：
--
作者：
Blaeser A;Duarte Campos DF;Weber M;Neuss S;Theek B;Fischer H;Jahnen-Dechent W
通讯作者：
Jahnen-Dechent W
影响因子：
6.2
作者：
Bermejo-Velasco, Daniel;Azemar, Alice;Varghese, Oommen P.
通讯作者：
Varghese, Oommen P.
影响因子：
10
作者：
Ali, Mohamed;Kumar, Anil P. R.;Lee, Sang Jin
通讯作者：
Lee, Sang Jin