Do the obese have lower body temperatures? A new look at a forgotten variable in energy balance.

Do the obese have lower body temperatures? A new look at a forgotten variable in energy balance.
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肥胖的人体温会低吗?

DOI:
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发表时间:
2009
影响因子:
--
通讯作者:
F. Turek
F. Turek
中科院分区:
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文献类型:
--
作者:
L. Landsberg;James B. Young;W. Leonard;R. Linsenmeier;F. Turek

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鉴于肥胖症在全球范围内的流行,了解肥胖症的发病机制现在比以往任何时候都更重要。本文探讨了核心温度在能量平衡中的潜在作用,并提出了一个假设,即基础温度和在各种情况下的温度响应的变化有助于提高肥胖状态的代谢效率。这一论点是基于产热在建立基础或静息代谢率方面的重要贡献,以及对温度变化在应对环境挑战中所起的适应作用的分析。如果这一假设得到证实,新的治疗方法可能随之而来。
Understanding the pathogenesis of obesity is now more important than ever, given the remarkable world-wide epidemic. This paper explores the potential role of core temperature in energy balance, and develops the hypothesis that basal temperature and changes in the temperature response in various situations contribute to the enhanced metabolic efficiency of the obese state. The argument is based on the important contribution that heat production makes in establishing the basal or resting metabolic rate, as well as on an analysis of the adaptive role played by changes in temperature in response to environmental challenge. If this hypothesis is validated, new therapeutic approaches may ensue.
DOI: 10.1016/j.cmet.2007.05.003
发表时间: 2007-06-01
期刊: CELL METABOLISM
影响因子: 29
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DOI: 10.1152/ajpendo.1984.247.2.e181
发表时间: 1984-01-01
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