Relationship between educational and occupational levels, and Chronic Kidney Disease in a multi-ethnic sample- The HELIUS study.
Relationship between educational and occupational levels, and Chronic Kidney Disease in a multi-ethnic sample- The HELIUS study.
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DOI：
10.1371/journal.pone.0186460
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发表时间：
2017
期刊：
影响因子：
3.7
通讯作者：
Agyemang C
中科院分区：
文献类型：
--
作者：
Adjei DN;Stronks K;Adu D;Snijder MB;Modesti PA;Peters RJG;Vogt L;Agyemang C
高收入国家的少数民族群体不成比例地受到慢性肾病（CKD）的影响，原因尚不清楚。我们评估了多种族人群中教育和职业水平与CKD的相关性。此外，我们评估了CKD患病率的种族不平等在多大程度上是由教育和职业水平造成的。对来自城市环境中健康生活（HELIUS）研究的基线数据进行横断面分析，研究对象为21，433名生活在荷兰阿姆斯特丹的18至70岁的成年人（4，525名荷兰人，3，027名南亚人，4，105名非洲人，2，314名加纳人，3，579名土耳其人和3，883名马达加斯加人）。使用2012年KDIGO（肾脏疾病：改善全球结局）CKD严重程度分类考虑了三种CKD结局。教育和职业水平之间的比较进行了逻辑回归分析。在调整性别和年龄后，在荷兰，低水平和中等水平的教育与CKD的高至极高风险的更高几率显著相关（比值比（OR）2.10，95% C.I.，1.37-2.95;或1.55，95% CI，1.03-2.34）。在少数民族群体中，低水平教育与高风险至极高风险CKD的高几率显著相关，但仅在南亚裔缅甸人中（OR 1.58，95% CI，1.06-2.34）。在职业水平与CKD风险的关系中发现了类似的结果。少数族裔群体的教育和职业水平较低是导致慢性肾脏病中观察到的种族不平等的部分原因。降低教育和职业水平低的少数民族人群的CKD风险可能有助于减少CKD及其相关并发症的种族不平等。
Ethnic minority groups in high-income countries are disproportionately affected by Chronic Kidney Disease (CKD) for reasons that are unclear. We assessed the association of educational and occupational levels with CKD in a multi-ethnic population. Furthermore, we assessed to what extent ethnic inequalities in the prevalence of CKD were accounted for by educational and occupational levels. Cross-sectional analysis of baseline data from the Healthy Life in an Urban Setting (HELIUS) study of 21,433 adults (4,525 Dutch, 3,027 South-Asian Surinamese, 4,105 African Surinamese, 2,314 Ghanaians, 3,579 Turks, and 3,883 Moroccans) aged 18 to 70 years living in Amsterdam, the Netherlands. Three CKD outcomes were considered using the 2012 KDIGO (Kidney Disease: Improving Global Outcomes) severity of CKD classification. Comparisons between educational and occupational levels were made using logistic regression analyses. After adjustment for sex and age, low-level and middle-level education were significantly associated with higher odds of high to very high-risk of CKD in Dutch (Odds Ratio (OR) 2.10, 95% C.I., 1.37–2.95; OR 1.55, 95% C.I., 1.03–2.34). Among ethnic minority groups, low-level education was significantly associated with higher odds of high to very-high-risk CKD but only in South-Asian Surinamese (OR 1.58, 95% C.I., 1.06–2.34). Similar results were found for the occupational level in relation to CKD risk. The lower educational and occupational levels of ethnic minority groups partly accounted for the observed ethnic inequalities in CKD. Reducing CKD risk in ethnic minority populations with low educational and occupational levels may help to reduce ethnic inequalities in CKD and its related complications.
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DOI：
10.1053/j.ajkd.2012.05.010
发表时间：
2012-11
期刊：
American journal of kidney diseases : the official journal of the National Kidney Foundation
影响因子：
--
作者：
Crews DC;McClellan WM;Shoham DA;Gao L;Warnock DG;Judd S;Muntner P;Miller ER;Powe NR
通讯作者：
Powe NR
影响因子：
5.4
作者：
Lynch, JW;Kaplan, GA;Salonen, JT
通讯作者：
Salonen, JT
DOI：
10.2215/cjn.00680208
发表时间：
2008-09-01
影响因子：
9.8
作者：
Bello, Aminu K.;Peters, Jean;El Nahas, Meguid
通讯作者：
El Nahas, Meguid
影响因子：
--
作者：
Krop, JS;Coresh, J;Brancati, FL
通讯作者：
Brancati, FL
影响因子：
2.3
作者：
Bailey PK;Tomson CR;Kinra S;Ebrahim S;Radhakrishna KV;Kuper H;Nitsch D;Ben-Shlomo Y
通讯作者：
Ben-Shlomo Y