Snoring Is Associated With Increased Risk of Stroke: A Cumulative Meta-Analysis.

Snoring Is Associated With Increased Risk of Stroke: A Cumulative Meta-Analysis.
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打鼾与中风风险增加相关:累积荟萃分析。

DOI:
10.3389/fneur.2021.574649
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发表时间:
2021
影响因子:
3.4
通讯作者:
Liu D
Liu D
中科院分区:
医学3区
文献类型:
--
作者:
Bai J;He B;Wang N;Chen Y;Liu J;Wang H;Liu D

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背景:几项研究表明打鼾会增加中风的风险;然而,结果并不一致。我们的目标是对评估打鼾症与成人中风风险之间关系的观察性研究进行系统回顾和荟萃分析。方法:应用计算机检索PubMed的相关研究。采用随机效应模型来汇总相对风险(RR),并使用累积荟萃分析方法中的林地来更好地说明汇总的RR是如何随着最新证据的积累而变化的。结果:文献检索得到符合我们纳入标准的16篇文章,共有3598名中风患者和145,901名参与者最终纳入我们的分析。在初步发现之后,发现了一致的关联趋势,摘要分析表明打鼾者中风风险增加46%(RR,1.46;95%CI,1.29-1.63;p<0.001)。结论:打鼾会显著增加中风的风险,最高可达46%。目前这项研究的重要性在于,我们提供了一个推定,以采取更积极的方法来应对鼾症患者中风风险的增加。
Background: Several studies have suggested that snoring is associated with an increased risk of stroke; however, the results are inconsistent. We aim to conduct a systematic review and meta-analysis of observational studies assessing the association between snoring and the risk of stroke in adults. Methods: We searched PubMed for relevant studies. A random-effect model was adopted to summary relative risks (RRs), and forest plots from a cumulative meta-analysis method were used for a better presentation of how the pooled RRs changed as updated evidence accumulated. Results: The literature search yielded 16 articles that met our inclusion criteria, and a total of 3,598 stroke patients and 145,901 participants were finally included in our analysis. A consistent trend toward association was found after the initial discovery, and the summary analysis indicated that snoring is associated with a 46% (RR, 1.46; 95%CI, 1.29–1.63; p < 0.001) increased risk of stroke. Conclusions: Snoring is associated with a significantly increased risk for stroke, up to 46%. The importance of the current study lies in that we provide an imputes to take a more active approach against the increased risk of stroke in snorers.
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发表时间: 2014-03
期刊: Sleep & breathing = Schlaf & Atmung
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