Rice Intake and Emerging Concerns on Arsenic in Rice: a Review of the Human Evidence and Methodologic Challenges.

Rice Intake and Emerging Concerns on Arsenic in Rice: a Review of the Human Evidence and Methodologic Challenges.
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大米中对砷的摄入量和新兴问题:对人类证据和方法论挑战的回顾。

DOI:
10.1007/s40572-019-00249-1
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发表时间:
2019-12
影响因子:
7.9
通讯作者:
Ahsan H
Ahsan H
中科院分区:
医学2区
文献类型:
--
作者:
Karagas MR;Punshon T;Davis M;Bulka CM;Slaughter F;Karalis D;Argos M;Ahsan H

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大米是全世界的主要主食,也是砷的膳食来源。因此,我们总结了关于大米消费是否与砷暴露相关的健康结果有关的流行病学证据。虽然流行病学研究报告说,更多的大米消费可能会增加某些慢性疾病的风险,即2型糖尿病,但大多数研究没有考虑大米的特定成分或其他砷暴露来源。根据水中砷浓度对大米摄入量进行分层的研究发现,有证据表明,心血管疾病风险、皮肤病变、鳞状细胞皮肤癌和膀胱癌的增加趋势与大米消费量增加有关。需要进一步研究,以了解从大米消费砷暴露的健康影响,考虑到所有来源的大米摄入量和潜在的混淆,其他饮食成分或污染物和砷暴露的来源,如水。
Rice is a major staple food worldwide and a dietary source of arsenic. We therefore summarized the state of the epidemiologic evidence on whether rice consumption relates to health outcomes associated with arsenic exposure. While epidemiologic studies have reported that higher rice consumption may increase the risk of certain chronic conditions, i.e. type 2 diabetes, most did not consider specific constituents of rice or other sources of arsenic exposure. Studies that examined rice intake stratified by water concentrations of arsenic, found evidence of increasing trends in cardiovascular disease risk, skin lesions, and squamous cell skin cancers and bladder cancer associated with higher rice consumption. Further studies are needed to understand the health impacts of arsenic exposure from rice consumption taking into account all sources of rice intake and potential confounding by other dietary constituents or contaminants and arsenic exposure from sources such as water.
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