Can anatomic alignment measured from a knee radiograph substitute for mechanical alignment from full limb films?
Can anatomic alignment measured from a knee radiograph substitute for mechanical alignment from full limb films?
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DOI：
10.1016/j.joca.2009.05.012
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发表时间：
2009-11
影响因子：
7
通讯作者：
OAI Investigators Group
中科院分区：
文献类型：
--
作者：
Felson DT;Cooke TD;Niu J;Goggins J;Choi J;Yu J;Nevitt MC;OAI Investigators Group
检查膝关节x线测量的解剖排列类别（内翻、中性、外翻）是否与全肢片测量的类似机械排列类别一致，以及内翻解剖排列失调是否预测膝关节x线和内翻机械排列上的内侧关节间隙损失。我们使用来自OAI（全肢和屈曲膝关节x线）的数据来检查解剖和机械对齐的一致性，并使用来自BOKS的数据来评估全肢机械对齐与膝关节x线解剖对齐与关节间隙损失的关系。四度偏移用于校正解剖对准的外翻角度。143名受试者的膝关节x光片和全肢片从OAI公开发布，内翻、中性和外翻对齐的一致性仅中等（κ= 0.43, p<.001）。在BOKS中，由全肢和膝关节x线分别测量的内翻机械和解剖对准与中性对准相比，均预测内侧关节间隙损失的风险较高(机械对准OR = 4.82 (95% CI 1.93, 12.00)，解剖对准OR = 4.25 （95% CI 2.08,8.72）。虽然膝关节x线与全肢片的对齐一致性只有中等程度，但从屈曲膝关节测量的内翻错位可以很好地预测进展的可能性。与完全伸直的膝关节相比，屈曲的膝关节对齐可能与膝关节炎风险更相关，但从短肢测量的对齐度并不能代替全肢对齐度。
To examine whether categories of anatomic alignment (varus, neutral,valgus) measured from knee x-rays agree with similar categories of mechanical alignment from the full limb film and whether varus anatomic malalignment predicts medial joint space loss on knee x-rays as well as varus mechanical alignment. We used data from the OAI (full limb and flexed knee x-rays) to examine agreement of anatomic and mechanical alignment and data from BOKS to evaluate the association of full limb mechanical alignment vs. knee x-ray anatomic alignment with joint space loss. A four degree offset was used to correct for the more valgus angulation of the anatomic alignment. Of 143 subjects whose knee x-rays and full limb films were publicly released from the OAI, the agreement of varus, neutral and valgus alignment was only moderate (κ= 0.43, p<.001). In BOKS, varus mechanical and anatomic alignments measured from full limb and knee x-rays respectively both predicted a high risk of medial joint space loss vs. neutral alignment (for mechanical alignment, OR = 4.82 (95% CI 1.93, 12.00) and for anatomic alignment OR = 4.25 (95% CI 2.08,8.72). While agreement of alignment from knee x-ray to full limb film was only moderate, varus malalignment measured from a flexed knee predicted the likelihood of progression well. Flexed knee alignment may be more relevant to knee OA risk than that of a fully extended knee, but a measurement of alignment from a short limb is an imperfect surrogate for full limb alignment.
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影响因子：
--
作者：
Kraus, VB;Vail, TP;McDaniel, G
通讯作者：
McDaniel, G
DOI：
10.2106/00004623-198769060-00012
发表时间：
1987-07-01
影响因子：
5.3
作者：
YOSHIOKA, Y;SIU, D;COOKE, TDV
通讯作者：
COOKE, TDV
影响因子：
--
作者：
Niu, J.;Zhang, Y. Q.;Torner, J.;Nevitt, M.;Lewis, C. E.;Aliabadi, P.;Sack, B.;Clancy, M.;Sharma, L.;Felson, D. T.
通讯作者：
Felson, D. T.
影响因子：
--
作者：
Hunter, David J.;Niu, Jingbo;Zhang, Yuqing
通讯作者：
Zhang, Yuqing
影响因子：
27.4
作者：
Miyazaki, T;Wada, M;Shimada, S
通讯作者：
Shimada, S