Subjective and Electroencephalographic Sleep Parameters in Children and Adolescents with Autism Spectrum Disorder: A Systematic Review.
Subjective and Electroencephalographic Sleep Parameters in Children and Adolescents with Autism Spectrum Disorder: A Systematic Review.
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DOI：
10.3390/jcm10173893
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发表时间：
2021-08-30
影响因子：
3.9
通讯作者：
Margari L
中科院分区：
文献类型：
--
作者：
Petruzzelli MG;Matera E;Giambersio D;Marzulli L;Gabellone A;Legrottaglie AR;Margari A;Margari L
背景资料：自闭症谱系障碍（ASD）儿童和青少年的睡眠问题通常表现为临床和病因成分之间复杂和多因素的相互作用。这些疾病与功能障碍有关，并引起严重的身体和精神痛苦。本研究的目的是更新现有文献中关于ASD儿童和青少年的客观和主观睡眠参数，从多导睡眠图或睡眠脑电图和睡眠相关问卷中推断信息。研究方法：我们对这一主题的病例对照研究进行了系统性综述，根据系统性综述和荟萃分析（PRISMA）指南的首选报告项目，对PubMed、Scopus和Web of Science数据库进行了基于网络的检索。结果如下：从20份调查结果报告中收集的数据显示，患有ASD的儿童和青少年的睡眠异常率高于正常发育的儿童。与主观父母报告的测量结果一致的宏观结构睡眠参数揭示了更大比例的夜间失眠症状。此外，睡眠微结构模式指出了ASD儿童大脑功能障碍和睡眠问题之间的双向关系。结论：今天的文献承认，客观和主观的睡眠困难更经常在ASD患者中被认识到，因此临床医生应该评估ASD临床人群的睡眠质量，同时考虑到对治疗策略的潜在影响。这将是值得在未来的研究，以探讨如何因素，如年龄，认知水平或ASD的严重程度可能与ASD睡眠异常。未来的研究应该直接评估睡眠改变是否可以代表ASD非典型大脑发育的特定标志物。
Background: Sleep problems have commonly manifested in children and adolescents with autism spectrum disorder (ASD) with a complex and multifactorial interaction between clinical and etiological components. These disorders are associated with functional impairment, and provoke significant physical and mental affliction. The purpose of this study is to update the existing literature about objective and subjective sleep parameters in children and adolescents with ASD, extrapolating information from polysomnography or sleep electroencephalography, and sleep related questionnaires. Methods: We have conducted a systematic review of case-control studies on this topic, performing a web-based search on PubMed, Scopus and the Web of Science databases according to the Preferred Reporting items for Systematic Review and Meta-analyses (PRISMA) guidelines. Results: Data collected from 20 survey result reports showed that children and adolescents with ASD experienced a higher rate of sleep abnormalities than in typically developing children. The macrostructural sleep parameters that were consistent with subjective parent reported measures unveil a greater percentage of nighttime signs of insomnia. Sleep microstructure patterns, in addition, pointed towards the bidirectional relationship between brain dysfunctions and sleep problems in children with ASD. Conclusions: Today’s literature acknowledges that objective and subjective sleep difficulties are more often recognized in individuals with ASD, so clinicians should assess sleep quality in the ASD clinical population, taking into consideration the potential implications on treatment strategies. It would be worthwhile in future studies to examine how factors, such as age, cognitive level or ASD severity could be related to ASD sleep abnormalities. Future research should directly assess whether sleep alterations could represent a specific marker for atypical brain development in ASD.
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影响因子：
4.4
作者：
Giannotti, Flavia;Cortesi, Flavia;Valente, Donatella
通讯作者：
Valente, Donatella
影响因子：
4.8
作者：
Kose, Sezen;Yilmaz, Helin;Ozbaran, N. Burcu
通讯作者：
Ozbaran, N. Burcu
影响因子：
3
作者：
Hornung, Taylor;Chan, Wen-Hsuan;Keehn, Brandon
通讯作者：
Keehn, Brandon
影响因子：
0.5
作者：
Devnani PA;Hegde AU
通讯作者：
Hegde AU
DOI：
10.1001/archpediatrics.2010.202
发表时间：
2010-11-01
影响因子：
--
作者：
Buckley, Ashura Williams;Rodriguez, Alcibiades J.;Swedo, Susan
通讯作者：
Swedo, Susan