Auditory projections to extrastriate visual cortex: connectional basis for multisensory processing in 'unimodal' visual neurons.
Auditory projections to extrastriate visual cortex: connectional basis for multisensory processing in 'unimodal' visual neurons.
复制标题
DOI：
10.1007/s00221-008-1493-7
复制
发表时间：
2008-10
影响因子：
2
通讯作者：
Meredith, M. Alex
中科院分区：
文献类型：
--
作者：
Clemo, H. Ruth;Sharma, Giriraj K.;Allman, Brian L.;Meredith, M. Alex
神经生理学研究最近记录了猫后外侧外侧上裂皮层（PLLS）的“单峰”视觉神经元的多感觉特性，该皮层是参与视觉运动处理的视网膜组织区域。在这个纹外视觉区域中，已经确定了一个区域，其中视觉和听觉刺激均独立有效地激活神经元（双峰区），以及第二个区域，其中视觉诱发活动受到并发听觉刺激的显着促进，但不受单独听觉刺激的影响（阈下多感觉区域）。鉴于它们的分布不同，我们在 21 只成年猫中使用生物素化葡聚糖胺 (BDA) 示踪剂方法检查了这些不同形式的跨模式收敛背后可能的皮质皮质连接。检查的听觉皮层区域包括前听觉区（AAF）、初级听觉皮层（AI）、背区（DZ）、次级听觉皮层（AII）、头侧侧裂上沟区（FRS）、前外裂区（FAES）和后听觉区（PAF）。在这些区域中，DZ、AI、AII 和 FAES 被发现投射到 PLLS 的双峰区和亚阈值区域。 PLLS 的跨模态输入的这种融合不仅表明复杂的听觉信息可以访问该区域，而且这些连接为多感官处理的不同形式（双模态与亚阈值）提供了基础，这可能有助于其在视觉运动处理中的功能作用。
Neurophysiological studies have recently documented multisensory properties in ‘unimodal’ visual neurons of the cat posterolateral lateral suprasylvian (PLLS) cortex, a retinotopically organized area involved in visual motion processing. In this extrastriate visual area, a region has been identified where both visual and auditory stimuli were independently effective in activating neurons (bimodal zone), as well as a second region where visually-evoked activity was significantly facilitated by concurrent auditory stimulation but was unaffected by auditory stimulation alone (subthreshold multisensory region). Given their different distributions, the possible corticocortical connectivity underlying these distinct forms of crossmodal convergence was examined using biotinylated dextran amine (BDA) tracer methods in 21 adult cats. The auditory cortical areas examined included the anterior auditory field (AAF), primary auditory cortex (AI), dorsal zone (DZ), secondary auditory cortex (AII), field of the rostral suprasylvian sulcus (FRS), field anterior ectosylvian sulcus (FAES) and the posterior auditory field (PAF). Of these regions, the DZ, AI, AII, and FAES were found to project to the both the bimodal zone and the subthreshold region of the PLLS. This convergence of crossmodal inputs to the PLLS suggests not only that complex auditory information has access to this region but also that these connections provide the substrate for the different forms (bimodal versus subthreshold) of multisensory processing which may facilitate its functional role in visual motion processing.
登录
查看更多内容
影响因子：
0.9
作者：
Clemo, HR;Meredith, MA
通讯作者：
Meredith, MA
影响因子：
2.5
作者：
Malhotra, S;Hall, AJ;Lomber, SG
通讯作者：
Lomber, SG
影响因子：
2.9
作者：
MIDDLEBROOKS, JC;DYKES, RW;MERZENICH, MM
通讯作者：
MERZENICH, MM
影响因子：
2.5
作者：
PALMER, LA;ROSENQUIST, AC;TUSA, RJ
通讯作者：
TUSA, RJ
影响因子：
1.9
作者：
GRANT, S;SHIPP, S
通讯作者：
SHIPP, S