Mice as experimental models for human physiology: when several degrees in housing temperature matter.

Mice as experimental models for human physiology: when several degrees in housing temperature matter.
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DOI:
10.1038/s42255-021-00372-0
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发表时间:
2021-04
期刊:
影响因子:
20.8
通讯作者:
MacDougald OA
MacDougald OA
中科院分区:
医学1区
文献类型:
--
作者:
Seeley RJ;MacDougald OA

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首先:小鼠和人类之间的一些“物种差异”可以通过将小鼠置于更温暖的温度下来减少。如果不能策略性地调高恒温器,可能会破坏小鼠研究结果转化为人类代谢疾病的见解。
Standfirst: Some “species differences” between mouse and human can be diminished simply by housing mice at warmer temperatures. Failure to strategically turn up the thermostat may undermine translation of findings in mice into insights on human metabolic diseases.
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