Prediction of preterm birth in twin gestations using biophysical and biochemical tests.
Prediction of preterm birth in twin gestations using biophysical and biochemical tests.
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DOI：
10.1016/j.ajog.2014.07.047
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发表时间：
2014-12
影响因子：
9.8
通讯作者：
Romero R
中科院分区：
文献类型：
--
作者：
Conde-Agudelo A;Romero R
本研究的目的是确定生物物理和生化测试的性能，以预测无症状和有症状的双胎妊娠妇女的早产。我们确定了总共19项用于预测早产的测试，主要用于无症状妇女。在这些妇女中，在怀孕25周之前用阴道超声测量宫颈长度似乎是预测早产的一个很好的测试。有证据表明，无症状双胎妊娠和宫颈短的妇女阴道给予孕酮可降低与自发性早产相关的新生儿发病率和死亡率，这增强了其临床潜力。其他建议用于早期识别无症状妇女早产风险增加的测试显示，预测准确性最低至中等。在这篇综述中评估的试验没有一项符合被认为在临床上有用的标准，以预测早产发作患者的早产。然而，宫颈阴道胎儿纤维连接蛋白测试阴性可能有助于确定下周内没有分娩风险的妇女，这可以避免不必要的住院和治疗。这篇综述强调需要开发准确的检测方法来预测双胎妊娠的早产。此外，根据检测结果对这些患者采取干预措施应与围产期结局的改善有关。
The objective of this study was to determine the performance of biophysical and biochemical tests for the prediction of preterm birth in both asymptomatic and symptomatic women with twin gestations. We identified a total of 19 tests proposed to predict preterm birth, mainly in asymptomatic women. In these women, a single measurement of cervical length with transvaginal ultrasound before 25 weeks of gestation appears to be a good test to predict preterm birth. Its clinical potential is enhanced by the evidence that vaginal progesterone administration in asymptomatic women with twin gestations and a short cervix reduces neonatal morbidity and mortality associated with spontaneous preterm delivery. Other tests proposed for the early identification of asymptomatic women at increased risk of preterm birth showed minimal to moderate predictive accuracy. None of the tests evaluated in this review meet the criteria to be considered clinically useful to predict preterm birth among patients with an episode of preterm labor. However, a negative cervicovaginal fetal fibronectin test could be useful in identifying women who are not at risk for delivering within the next week, which could avoid unnecessary hospitalization and treatment. This review underscores the need to develop accurate tests for predicting preterm birth in twin gestations. Moreover, the use of interventions in these patients based on test results should be associated with the improvement of perinatal outcomes.
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影响因子：
1.8
作者：
Chaiworapongsa, T;Romero, R;Kuivaniemi, H
通讯作者：
Kuivaniemi, H
DOI：
10.1111/j.1600-0897.1993.tb00619.x
发表时间：
1993-09-01
影响因子：
3.6
作者：
BAUMANN, P;ROMERO, R;FIDEL, P
通讯作者：
FIDEL, P
影响因子：
4
作者：
Aboulghar, Mona M.;Aboulghar, Mohamed A.;Mansour, Ragaa T.
通讯作者：
Mansour, Ragaa T.
DOI：
10.1375/twin.4.3.159
发表时间：
2001-06-01
期刊：
Twin research : the official journal of the International Society for Twin Studies
影响因子：
--
作者：
Di Renzo, G C;Luzietti, R;Clerici, G
通讯作者：
Clerici, G
影响因子：
1.8
作者：
Esplin, MS;Romero, R;Adashi, EY
通讯作者：
Adashi, EY