Roadmap on biology in time varying environments.

Roadmap on biology in time varying environments.
复制标题

DOI:
10.1088/1478-3975/abde8d
复制
发表时间:
2021-05-17
期刊:
影响因子:
2
通讯作者:
Goldenfeld N
Goldenfeld N
中科院分区:
生物学4区
文献类型:
--
作者:
Murugan A;Husain K;Rust MJ;Hepler C;Bass J;Pietsch JMJ;Swain PS;Jena SG;Toettcher JE;Chakraborty AK;Sprenger KG;Mora T;Walczak AM;Rivoire O;Wang S;Wood KB;Skanata A;Kussell E;Ranganathan R;Shih HY;Goldenfeld N

文献摘要

参考文献

被引文献

相似文献

生物有机体经历不断变化的环境,从进食带来的生理突然变化,到太阳的定期升起和落下,再到进化时间尺度上的生态变化。生物体已经进化到在这个不断变化的世界中茁壮成长,但生物体塑造和被时变环境塑造的一般原则仍然难以捉摸。我们的理解在没有时间尺度分离的中间状态中特别差,在那里,环境的变化与生理或进化反应的时间尺度相同。系统地表征对动态环境的响应的实验是具有挑战性的,因为这样的环境固有地是高维的。该路线图涉及时变环境在不同尺度的生物现象中所发挥的独特作用,从生理学到进化,旨在强调这一新兴研究领域所面临的共性和挑战。
Biological organisms experience constantly changing environments, from sudden changes in physiology brought about by feeding, to the regular rising and setting of the Sun, to ecological changes over evolutionary timescales. Living organisms have evolved to thrive in this changing world but the general principles by which organisms shape and are shaped by time varying environments remain elusive. Our understanding is particularly poor in the intermediate regime with no separation of timescales, where the environment changes on the same timescale as the physiological or evolutionary response. Experiments to systematically characterize the response to dynamic environments are challenging since such environments are inherently high dimensional. This roadmap deals with the unique role played by time varying environments in biological phenomena across scales, from physiology to evolution, seeking to emphasize the commonalities and the challenges faced in this emerging area of research.
DOI: 10.1016/j.coi.2018.04.025
发表时间: 2018-08
影响因子: 7
作者:
Andrabi R;Bhiman JN;Burton DR
通讯作者: Burton DR
DOI: 10.1038/nrm4041
发表时间: 2015-09
期刊: Nature reviews. Molecular cell biology
影响因子: --
作者:
Duncombe TA;Tentori AM;Herr AE
通讯作者: Herr AE
昼夜主义代谢的地图集揭示了时钟之间全系统的协调和通信。
DOI: 10.1016/j.cell.2018.08.042
发表时间: 2018-09-06
期刊: Cell
影响因子: 64.5
作者:
Dyar KA;Lutter D;Artati A;Ceglia NJ;Liu Y;Armenta D;Jastroch M;Schneider S;de Mateo S;Cervantes M;Abbondante S;Tognini P;Orozco-Solis R;Kinouchi K;Wang C;Swerdloff R;Nadeef S;Masri S;Magistretti P;Orlando V;Borrelli E;Uhlenhaut NH;Baldi P;Adamski J;Tschöp MH;Eckel-Mahan K;Sassone-Corsi P
通讯作者: Sassone-Corsi P
DOI: 10.1126/science.aad3292
发表时间: 2016-01-01
期刊: Science (New York, N.Y.)
影响因子: --
作者:
Baym M;Stone LK;Kishony R
通讯作者: Kishony R
DOI: 10.1016/j.cmet.2018.08.004
发表时间: 2019-02-05
期刊: Cell metabolism
影响因子: 29
作者:
Chaix A;Lin T;Le HD;Chang MW;Panda S
通讯作者: Panda S