Pressure-Mediated Reflection Spectroscopy Criterion Validity as a Biomarker of Fruit and Vegetable Intake: A 2-Site Cross-Sectional Study of 4 Racial or Ethnic Groups.
Pressure-Mediated Reflection Spectroscopy Criterion Validity as a Biomarker of Fruit and Vegetable Intake: A 2-Site Cross-Sectional Study of 4 Racial or Ethnic Groups.
复制标题
DOI：
10.1093/jn/nxab349
复制
发表时间：
2022-01-11
期刊：
影响因子：
--
通讯作者：
Laska MN
中科院分区：
文献类型：
--
作者：
Jilcott Pitts SB;Moran NE;Wu Q;Harnack L;Craft NE;Hanchard N;Bell R;Moe SG;Johnson N;Obasohan J;Carr-Manthe PL;Laska MN
实地营养研究需要有效的水果和蔬菜（FV）摄入量生物标志物。以血浆类胡萝卜素和自我报告类胡萝卜素摄入量分别作为主要和次要标准措施，检验压力介导反射光谱作为FV摄入量替代措施的标准相关有效性。在北卡罗莱纳州和明尼苏达州招募了年龄在18-65岁、自我认同为非裔美国人/黑人（n = 61）、亚洲人（n = 53）、白人（n = 70）或西班牙裔（n = 29）的健康成年人。通过压力介导反射光谱（Veggie Meter）评估皮肤类胡萝卜素，通过分光光度计评估皮肤黑色素，通过hplc -光电二极管阵列检测血浆总类胡萝卜素浓度。使用半定量FFQ评估自我报告的类胡萝卜素和脂肪摄入量。皮肤类胡萝卜素、血浆类胡萝卜素、FV和类胡萝卜素摄入量之间的关系，与种族或民族、年龄、性别、体重状况、胆固醇和黑色素指数的差异，通过双变量相关性和调整的多变量线性回归进行了检验。皮肤和总血浆类胡萝卜素之间的总体未调整相关性为r = 0.71，范围从0.64（非西班牙裔黑人）到0.80（西班牙裔）。皮肤类胡萝卜素与自我报告的FV摄入量之间的相关性范围从0.24（非西班牙裔黑人）到0.53（非西班牙裔白人），总体相关性r = 0.35。在调整了年龄、性别、种族或民族和BMI的模型中，皮肤类胡萝卜素与血浆类胡萝卜素（R2 = 0.55）、FV （R2 = 0.17）和类胡萝卜素摄入量（R2 = 0.20）相关。对于血浆类胡萝卜素和FV测量，与皮肤类胡萝卜素的关联并不因种族而异，但这些关系确实因皮肤黑色素而异——黑色素较低的人皮肤和血浆类胡萝卜素之间的相关性较低。反射光谱评估皮肤类胡萝卜素可能是测量血浆类胡萝卜素的合理替代方法，类胡萝卜素是一种用于近似FV摄入量的生物标志物。
Valid biomarkers of fruit and vegetable (FV) intake are needed for field-based nutrition research. To examine criterion-related validity of pressure-mediated reflection spectroscopy as a proxy measure of FV intake, using plasma carotenoids and self-reported FV and carotenoid intake as primary and secondary criterion measures, respectively. Healthy adults 18–65 y of age, self-identifying as African American/black (n = 61), Asian (n = 53), white (n = 70), or Hispanic (n = 29), in North Carolina and Minnesota were recruited. Skin carotenoids were assessed via pressure-mediated reflection spectroscopy (Veggie Meter), skin melanin via spectrophotometer, and total plasma carotenoid concentration by HPLC–photodiode array detection. Self-reported carotenoid and FV intake was assessed using a semiquantitative FFQ. Relations between skin carotenoids, plasma carotenoids, FV, and carotenoid intake, with differences by race or ethnicity, age, sex, weight status, cholesterol, and melanin index, were examined by bivariate correlations and adjusted multivariate linear regressions. The overall unadjusted correlation between skin and total plasma carotenoids was r = 0.71 and ranged from 0.64 (non-Hispanic black) to 0.80 (Hispanic). Correlations between skin carotenoids and self-reported FV intake ranged from 0.24 (non-Hispanic black) to 0.53 (non-Hispanic white), with an overall correlation of r = 0.35. In models adjusted for age, sex, racial or ethnic group, and BMI, skin carotenoids were associated with plasma carotenoids (R2 = 0.55), FV (R2 = 0.17), and carotenoid intake (R2 = 0.20). For both plasma carotenoid and FV measures, associations with skin carotenoids did not vary by race, but these relations did differ by skin melanin—those with lower melanin had a lower correlation between skin and plasma carotenoids. Reflection spectroscopy–assessed skin carotenoids may be a reasonable alternative to measurement of plasma carotenoids, a biomarker used to approximate FV intake.
登录
查看更多内容
影响因子：
5
作者：
Harnack, L;Himes, JH;Weber, JL
通讯作者：
Weber, JL
DOI：
10.1016/j.jand.2014.04.026
发表时间：
2014-08-01
影响因子：
4.8
作者：
Aguilar, Sheryl S.;Wengreen, Heidi J.;Gast, Julie
通讯作者：
Gast, Julie
影响因子：
5.2
作者：
Bondy, S. J.;Victor, J. C.;Diemert, L. M.
通讯作者：
Diemert, L. M.
影响因子：
5
作者：
Freedman, Laurence S.;Commins, John M.;Willett, Walter
通讯作者：
Willett, Walter
影响因子：
2.6
作者：
Bayles J;Peterson AD;Jilcott Pitts S;Bian H;Goodell LS;Burkholder S;Hegde AV;Stage VC
通讯作者：
Stage VC