Adaptive evolution of mitochondrial energy metabolism genes associated with increased energy demand in flying insects.
Adaptive evolution of mitochondrial energy metabolism genes associated with increased energy demand in flying insects.
复制标题
与飞行昆虫能量需求增加相关的线粒体能量代谢基因的适应性进化
DOI：
10.1371/journal.pone.0099120
复制
发表时间：
2014
期刊：
影响因子：
3.7
通讯作者：
Yang G
中科院分区：
文献类型：
--
作者：
Yang Y;Xu S;Xu J;Guo Y;Yang G
昆虫的飞行能力在无脊椎动物中是独一无二的，这就提出了有趣的问题，即昆虫的能量代谢是如何随着飞行而进化和变化的。虽然生理研究表明飞行和非飞行昆虫的能量消耗不同，但昆虫分子能量代谢机制的进化在很大程度上仍未被探索。考虑到大约95%的三磷酸腺苷(ATP)是由线粒体通过氧化磷酸化提供的，我们检测了13个线粒体蛋白编码基因，以检验昆虫中是否发生了能量代谢相关基因的适应性进化。分析表明，线粒体DNA蛋白编码基因受到来自翼目动物最后一个共同祖先的正选择，翼目动物进化出了原始的飞行能力。在有飞行能力的昆虫中也发现了正选择，而在翅膀退化的不会飞的昆虫中没有发现明显的选择迹象。此外，在新翅目最后一个共同祖先中也发现了显著的正选择，从直接飞行方式转变为间接飞行方式。有趣的是，在间接飞行的昆虫中检测到更多积极选择的基因，而不是直接飞行的昆虫中，表明在能量消耗更高的昆虫中有更强的选择压力。总之，参与能量代谢的线粒体蛋白编码基因是适应进化的目标，以响应昆虫飞行能力进化过程中产生的更高的能量需求。
Insects are unique among invertebrates for their ability to fly, which raises intriguing questions about how energy metabolism in insects evolved and changed along with flight. Although physiological studies indicated that energy consumption differs between flying and non-flying insects, the evolution of molecular energy metabolism mechanisms in insects remains largely unexplored. Considering that about 95% of adenosine triphosphate (ATP) is supplied by mitochondria via oxidative phosphorylation, we examined 13 mitochondrial protein-encoding genes to test whether adaptive evolution of energy metabolism-related genes occurred in insects. The analyses demonstrated that mitochondrial DNA protein-encoding genes are subject to positive selection from the last common ancestor of Pterygota, which evolved primitive flight ability. Positive selection was also found in insects with flight ability, whereas no significant sign of selection was found in flightless insects where the wings had degenerated. In addition, significant positive selection was also identified in the last common ancestor of Neoptera, which changed its flight mode from direct to indirect. Interestingly, detection of more positively selected genes in indirect flight rather than direct flight insects suggested a stronger selective pressure in insects having higher energy consumption. In conclusion, mitochondrial protein-encoding genes involved in energy metabolism were targets of adaptive evolution in response to increased energy demands that arose during the evolution of flight ability in insects.
登录
查看更多内容
影响因子：
2.9
作者：
Carroll, Joe;Fearnley, Ian M.;Walker, John E.
通讯作者：
Walker, John E.
影响因子：
3.7
作者：
Gonçalves RL;Machado AC;Paiva-Silva GO;Sorgine MH;Momoli MM;Oliveira JH;Vannier-Santos MA;Galina A;Oliveira PL;Oliveira MF
通讯作者：
Oliveira MF
影响因子：
64.8
作者：
Engel, MS;Grimaldi, DA
通讯作者：
Grimaldi, DA
影响因子：
37.3
作者：
Carew JS;Huang P
通讯作者：
Huang P
DOI：
10.1046/j.1095-8312.2003.00217.x
发表时间：
2003-09-01
影响因子：
1.9
作者：
Mayhew, PJ
通讯作者：
Mayhew, PJ