Practical applicability of genetics for the prevention and treatment of hypertension.
Practical applicability of genetics for the prevention and treatment of hypertension.
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DOI：
10.1111/jch.14400
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发表时间：
2022-03
期刊：
影响因子：
--
通讯作者：
Silva AS
中科院分区：
文献类型：
--
作者：
Silva AS
Zou和他的同事们在本期的《临床高血压杂志》上发表了他们的一项研究结果，他们发现人类corin基因多态性与血压控制有关，更具体地说，与盐敏感性有关。在此之前不久，一项文献综述表明，另外18个基因也与盐敏感性有关，但corin基因。新发现的基因的这种动态性显示了研究动脉高血压遗传控制的复杂性，并解释了其已知的前促血脂特征。在这篇评论中，Zou及其同事的研究被置于高血压遗传学的最新证据的背景下，并在遗传学在预防和治疗高血压中的临床应用的背景下提出了这项研究和其他研究的未来前景。
Zou and colleagues are publishing in this issue of The Journal of Clinical Hypertension, result of one of their studies in which they found that human corin genetic polymorphisms is involved in blood pressure control, more specifically in salt sensitivity. It is being published in this journal shortly after a literature review indicated another 18 genes were also involved in salt sensitivity, however corin gene. This dynamism of newly discovered genes shows the complexity of studying the genetic control of arterial hypertension and explains its known preliotropic characteristic. In this commentary, the study by Zou and colleagues is placed in the context of recent evidence on the genetics of high blood pressure and the future perspectives resulting from this and other studies are presented in the context of the clinical application of genetics in the prevention and treatment of high blood pressure.
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影响因子：
2.8
作者：
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通讯作者：
Pereira, Rafael
影响因子：
3.9
作者：
Roche, HM
通讯作者：
Roche, HM
影响因子：
4
作者：
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通讯作者：
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影响因子：
5.6
作者：
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通讯作者：
Souza BSF
DOI：
10.1038/nrneph.2015.176
发表时间：
2016-02
期刊：
Nature reviews. Nephrology
影响因子：
--
作者：
Cooper-DeHoff RM;Johnson JA
通讯作者：
Johnson JA