Functional divergence in gastrointestinal microbiota in physically-separated genetically identical mice.
Functional divergence in gastrointestinal microbiota in physically-separated genetically identical mice.
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DOI:
10.1038/srep05437
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发表时间:
2014-06-25
影响因子:
4.6
通讯作者:
Bruce KD
中科院分区:
文献类型:
--
作者:
Rogers GB;Kozlowska J;Keeble J;Metcalfe K;Fao M;Dowd SE;Mason AJ;McGuckin MA;Bruce KD
Despite the fundamental contribution of the gut microbiota to host physiology, the extent of its variation in genetically-identical animals used in research is not known. We report significant divergence in both the composition and metabolism of gut microbiota in genetically-identical adult C57BL/6 mice housed in separate controlled units within a single commercial production facility. The reported divergence in gut microbiota has the potential to confound experimental studies using mammalian models.
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影响因子:
8.3
作者:
Rogers, Geraint B;Zain, Nur Masirah M;Serisier, David J
通讯作者:
Serisier, David J
影响因子:
6.5
作者:
Capone, Kimberly A.;Dowd, Scot E.;Stamatas, Georgios N.;Nikolovski, Janeta
通讯作者:
Nikolovski, Janeta
DOI:
10.1038/ismej.2010.162
发表时间:
2011-04
期刊:
The ISME journal
影响因子:
--
作者:
通讯作者:
--
影响因子:
11
作者:
Haegeman, Bart;Hamelin, Jerome;Weitz, Joshua S.
通讯作者:
Weitz, Joshua S.
影响因子:
6.4
作者:
Claus SP;Ellero SL;Berger B;Krause L;Bruttin A;Molina J;Paris A;Want EJ;de Waziers I;Cloarec O;Richards SE;Wang Y;Dumas ME;Ross A;Rezzi S;Kochhar S;Van Bladeren P;Lindon JC;Holmes E;Nicholson JK
通讯作者:
Nicholson JK