Association of neighborhood deprivation with pulmonary function measures among participants in the Gulf Long-Term Follow-up Study.
Association of neighborhood deprivation with pulmonary function measures among participants in the Gulf Long-Term Follow-up Study.
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DOI：
10.1016/j.envres.2021.111704
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发表时间：
2021-11
影响因子：
8.3
通讯作者：
Sandler DP
中科院分区：
文献类型：
--
作者：
Lawrence KG;Werder EJ;Sandler DP
个体水平的社会经济地位（SES）已被证明是肺功能的重要决定因素。邻里水平的SES因素可能会增加心理和生理压力，也可能反映其他可能对肺功能产生不利影响的暴露，但很少有研究考虑邻里因素。我们的目的是评估社区水平SES与肺功能之间的关系。我们横断面分析了海湾长期随访研究参与者的6168个肺活量测定结果，该研究是在美国历史上最大的海上石油泄漏事件发生后招募的一大群成年人。结果包括1秒用力呼气量（FEV1; mL）、用力肺活量（FVC; mL）和FEV1/FVC比值（%）。邻里剥夺是通过将参与者的家庭住址与现有的区域剥夺指数（ADI）联系起来来衡量的，并分为四分位数。在入组时使用结构化问卷收集个人层面的SES测量，包括收入、受教育程度和经济压力。我们使用多水平回归来估计ADI四分位数与每个肺功能测量之间的关联。较大的邻域剥夺与较低的FEV1相关：βQ2vsQ1:−30 mL (95% CI:−97,36),βQ3vsQ1:−70 mL （95% CI:−135,−4）和βQ4vsQ1:−104 mL （95% CI:−171,−36）。植被覆盖度与邻里剥夺表现出相似的关联模式。与FEV1/FVC比值无关联。邻里剥夺（一种综合经济和其他压力因素的测量方法）与较低的FEV1和FVC相关，其关联程度达到了临床有意义的水平。即使在调整了个人层面的SES因素后，这种社区SES测量的影响仍然存在。
Individual-level socioeconomic status (SES) has been shown to be an important determinant of lung function. Neighborhood level SES factors may increase psychological and physiologic stress and may also reflect other exposures that can adversely affect lung function, but few studies have considered neighborhood factors. Our aim was to assess the association between neighborhood-level SES and lung function. We cross-sectionally analyzed 6,168 spirometry test results from participants in the Gulf long-term Follow-up Study, a large cohort of adults enrolled following the largest maritime oil spill in US history. Outcomes of interest included the forced expiratory volume in one second (FEV1; mL), the forced vital capacity (FVC; mL), and the FEV1/FVC ratio (%). Neighborhood deprivation was measured by linking participant home addresses to an existing Area Deprivation Index (ADI) and categorized into quartiles. Individual-level SES measures were collected at enrollment using a structured questionnaire and included income, educational attainment, and financial strain. We used multilevel regression to estimate associations between ADI quartiles and each lung function measure. Greater neighborhood deprivation was associated with lower FEV1: βQ2vsQ1: −30 mL (95% CI: −97, 36), βQ3vsQ1: −70 mL (95% CI: −135, −4) and βQ4vsQ1: −104 mL (95% CI: −171, −36). FVC showed similar patterns of associations with neighborhood deprivation. No associations with the FEV1/FVC ratio were observed. Neighborhood deprivation, a measure incorporating economic and other stressors, was associated with lower FEV1 and FVC, with magnitudes of associations reaching clinically meaningful levels. The impact of this neighborhood SES measure persisted even after adjustment for individual-level SES factors.
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影响因子：
39.2
作者：
Kind AJ;Jencks S;Brock J;Yu M;Bartels C;Ehlenbach W;Greenberg C;Smith M
通讯作者：
Smith M
影响因子：
4.3
作者：
Miller, Martin R.;Pedersen, Ole F.;Vestbo, Jorgen
通讯作者：
Vestbo, Jorgen
影响因子：
8
作者：
Beck, Andrew F.;Huang, Bin;Kahn, Robert S.
通讯作者：
Kahn, Robert S.
DOI：
10.1164/ajrccm.155.1.9001300
发表时间：
1997-01-01
影响因子：
24.7
作者：
AckermannLiebrich, U;Leuenberger, P;Zemp, E
通讯作者：
Zemp, E
DOI：
10.1111/j.1749-6632.1999.tb08119.x
发表时间：
1999-01-01
期刊：
SOCIOECONOMIC STATUS AND HEALTH IN INDUSTRIAL NATIONS
影响因子：
--
作者：
Cohen, S
通讯作者：
Cohen, S