Gestational diabetes and cardiovascular risk factors and disease in U.S. Hispanics/Latinas in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).

Gestational diabetes and cardiovascular risk factors and disease in U.S. Hispanics/Latinas in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).
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DOI:
10.1080/03630242.2018.1500415
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发表时间:
2019-05
期刊:
影响因子:
1.6
通讯作者:
Llabre MM
Llabre MM
中科院分区:
医学4区
文献类型:
--
作者:
Perera MJ;Reina SA;Elfassy T;Potter JE;Sotres Alvarez D;Simon MA;Isasi CR;Stuebe AM;Schneiderman N;Llabre MM

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比较有和无妊娠期糖尿病(GDM)史的美国西班牙裔/拉丁裔人群的心血管风险和疾病患病率。分析了2008-2011年西班牙裔社区健康研究/拉丁裔研究中8262例(305例有GDM病史)年龄在20-73岁的经产妇女的横断面数据。比较有和无GDM病史的妇女的社会人口统计学、心血管危险因素和标准化访谈和空腹血液检查的疾病数据,使用卡方检验、t检验和Logistic回归确定比值比(OR)和95%置信区间(CI)。调整协变量后,与无GDM病史的女性相比,有GDM病史的女性:年轻(平均值=39.1 [95% CI=37.8,41.6] vs. 45.5年[95% CI=44.9,46.1]),更有可能有健康保险(68.1% [95% CI= 60.3%,76.0%]对比54.9% [95% CI= 52.8%,57.1%]);腰围更大(平均值=102.3,[95% CI=100.2,104.3] vs. 98.1 cm [95% CI=97.4,98.5])和空腹血糖较高(116.0 [95% CI=107.8,124.3] vs. 104.2 mg/dL [95% CI=103.4,105.1]);并且患有代谢综合征(OR=1.7 [95% CI=1.2-2.6])或糖尿病(OR=3.3 [95% CI=2.2-4.8])的几率更高。心脏病和脑血管病的患病率相似。GDM病史与糖尿病呈正相关,但与心血管疾病无关。
To compare cardiovascular risk and disease prevalence in U.S. Hispanics/Latinas with and without a history of gestational diabetes mellitus (GDM). Cross-sectional data from 2008–2011 were analyzed for 8262 (305 with GDM history) parous women, aged 20–73 years, from the Hispanic Community Health Study/Study of Latinos. Women with and without a history of GDM were compared on socio-demographic, cardiovascular risk factor, and disease data from standardized interviews and fasting blood tests, using chi-square tests, t-tests, and logistic regressions to determine odds ratios (OR) and 95% confidence intervals (CI). Adjusting for covariates, compared to those without a history of GDM, women with a history of GDM: were younger (mean=39.1 [95% CI=37.8, 41.6] vs. 45.5 years [95% CI=44.9, 46.1]) and more likely to have health insurance (68.1% [95% CI=60.3%, 76.0%] vs. 54.9% [95% CI=52.8%, 57.1%]); had greater waist circumference (mean=102.3, [95% CI=100.2, 104.3] vs. 98.1 cm [95% CI=97.4, 98.5]) and higher fasting glucose (116.0 [95% CI=107.8, 124.3] vs. 104.2 mg/dL [95% CI=103.4, 105.1]); and had higher odds of having metabolic syndrome (OR=1.7 [95% CI=1.2–2.6]) or diabetes (OR=3.3 [95% CI=2.2–4.8]). Prevalences of heart and cerebrovascular disease were similar. GDM history was positively associated with diabetes but not with cardiovascular disease.
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