Parity and diabetes risk among hispanic women from Colombia: cross-sectional evidence.
Parity and diabetes risk among hispanic women from Colombia: cross-sectional evidence.
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DOI：
10.1186/s13098-015-0001-z
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发表时间：
2015
影响因子：
4.8
通讯作者：
Cure-Cure C
中科院分区：
文献类型：
--
作者：
Cure P;Hoffman HJ;Cure-Cure C
已在发达国家、新加坡和中国妇女中研究了产次与2型糖尿病之间的关系，但未在西班牙裔妇女中研究。在此，我们评估了一组来自哥伦比亚的西班牙裔绝经后妇女的产次（活产数）与糖尿病之间的关系。在本文中，我们评估了来自哥伦比亚的1，795名妇女的产次与糖尿病之间的关系。妇女按生育类别（0胎、1胎或2胎、3-5胎、6胎或>胎）分类。记录糖尿病病史和人体测量特征。在控制了年龄、体重指数（BMI）、腰臀比（WHR）和糖尿病家族史等变量后，采用双变量和多变量模型进行Logistic回归分析，以发现产次与糖尿病之间的关系。在我们的研究中，与未生育的妇女相比，在调整了年龄、BMI和糖尿病家族史后，经产妇女组的产次与糖尿病之间存在关联（参照组）[1-2胎vs.参照OR 5.2（95 CI 1.2-22.9），3-5次分娩与参照OR 5.5（1.3-23.0）和≥6次分娩与参照OR 7.5（1.8-31.8））。在多变量分析中，两组中的相关性保持不变[OR 5.0（1.1-22.9）和5.3（1.2-23.5）]，分别为1或2胎和6或>胎与0胎。阳性糖尿病家族史和腰臀比也与糖尿病风险增加相关[OR分别为4.6（3.0-7.0）和4.1（2.0-8.1）]。在绝经后的西班牙裔妇女中，多产，以及糖尿病家族史和高腰臀比与糖尿病风险较高相关。
The association between parity and type 2 diabetes has been studied in developed countries and in Singapore and Chinese women but not in Hispanics. Herein we evaluated the association between parity (number of live births) with diabetes in a group of Hispanic postmenopausal women from Colombia. Herein we evaluated the association between parity and diabetes in a population of 1,795 women from Colombia. Women were divided in birth categories (0 [referent], 1 or 2, 3–5, 6 or > births). Medical history of diabetes and anthropometric characteristics were recorded. Logistic regressions were performed in order to find the association between parity and diabetes in bivariable and multivariable models after controlling for age, body mass index (BMI), waist hip ratio (WHR) and diabetes family history, among other variables. In our study, there was an association between parity and diabetes after adjusting for age, BMI and diabetes family history in the multiparous women groups when compared to the women with no births (Referent group) [1–2 births vs. referent OR 5.2 (95 CI 1.2–22.9), 3–5 births vs. referent OR 5.5 (1.3–23.0) and ≥6 births vs. referent OR 7.5 (1.8–31.8), respectively]. The association was maintained in two of the groups in the multivariable analysis [OR 5.0 (1.1–22.9) and 5.3 (1.2–23.5)], for 1 or 2 births and 6 or > births versus 0 births, respectively. Positive diabetes family history and WHR were also associated with an increased risk of diabetes [OR 4.6 (3.0–7.0) and 4.1 (2.0–8.1), respectively]. In postmenopausal Hispanic women, multiparity, as well as a positive family history of diabetes and a high waist-hip ratio were associated with higher diabetes risk.
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DOI：
10.1111/1471-0528.12364
发表时间：
2013-11
期刊：
BJOG : an international journal of obstetrics and gynaecology
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作者：
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