Meeting Summary: Global Vaccine and Immunization Research Forum, 2021.
Meeting Summary: Global Vaccine and Immunization Research Forum, 2021.
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DOI：
10.1016/j.vaccine.2023.02.028
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发表时间：
2023-03-10
期刊：
影响因子：
5.5
通讯作者：
Hall, Fenton
中科院分区：
文献类型：
--
作者：
Ford, Andrew;Hwang, Angela;Mo, Annie X.;Baqar, Shahida;Touchette, Nancy;Deal, Carolyn;King, Deborah;Earle, Kristen;Giersing, Birgitte;Dull, Peter;Hall, Fenton
全球合作和数十年的疫苗研究继续产生效益。这些投资和经验使得我们能够对 COVID-19 做出快速反应。 COVID-19 取得的进展应适用于其他疫苗和应急准备。 2021 年全球疫苗和免疫研究论坛强调了疫苗和免疫研究和开发方面的重大进展和最新进展，严格审查了从 COVID-19 疫苗计划中吸取的经验教训，并展望了这十年的机遇。对于 COVID-19，几十年来对基础和转化研究、新技术平台和针对原型病原体的疫苗的投资促成了全球的快速反应。前所未有的全球协调和伙伴关系在研制和提供 COVID-19 疫苗方面发挥了重要作用。需要进一步改进产品属性，例如可交付性和公平获得疫苗的机会。其他优先领域的进展包括：由于缺乏预防感染的功效而停止了两项人类免疫缺陷病毒疫苗试验；两种结核疫苗的 2 期试验取得了有希望的疗效结果；在三个国家试点实施最先进的疟疾候选疫苗；以单剂量方案给予人乳头瘤病毒疫苗的试验；以及新型口服脊髓灰质炎 2 型疫苗的紧急使用清单。正在制定更系统、更主动的方法，以促进疫苗的使用和需求，协调公共和私营部门的投资优先事项，并加快政策制定。与会者强调，解决地方病问题与应急准备和大流行病应对相互交织，因此一个领域的进步为另一个领域创造了机会。在这十年中，应对 COVID-19 大流行所取得的进展应该会加速其他疾病疫苗的供应，有助于为未来的大流行做好准备，并有助于实现 2030 年免疫议程的影响和公平。
Global collaboration and decades of vaccine research continue to yield benefits. Such investments and experience enabled a rapid response to COVID-19. Advances made due to COVID-19 should be applied to other vaccines and to emergency preparedness. The 2021 Global Vaccine and Immunization Research Forum highlighted the considerable advances and recent progress in research and development for vaccines and immunization, critically reviewed lessons learned from COVID-19 vaccine programs, and looked ahead to opportunities for this decade. For COVID-19, decades of investments in basic and translational research, new technology platforms, and vaccines targeting prototype pathogens enabled a rapid, global response. Unprecedented global coordination and partnership have played an essential role in creating and delivering COVID-19 vaccines. More improvement is needed in product attributes such as deliverability, and in equitable access to vaccines. Developments in other priority areas included: the halting of two human immunodeficiency virus vaccine trials due to lack of efficacy in preventing infection; promising efficacy results in Phase 2 trials of two tuberculosis vaccines; pilot implementation of the most advanced malaria vaccine candidate in three countries; trials of human papillomavirus vaccines given in single-dose regimens; and emergency use listing of a novel, oral poliomyelitis type 2 vaccine. More systematic, proactive approaches are being developed for fostering vaccine uptake and demand, aligning on priorities for investment by the public and private sectors, and accelerating policy making. Participants emphasized that addressing endemic disease is intertwined with emergency preparedness and pandemic response, so that advances in one area create opportunities in the other. In this decade, advances made in response to the COVID-19 pandemic should accelerate availability of vaccines for other diseases, contribute to preparedness for future pandemics, and help to achieve impact and equity under Immunization Agenda 2030.
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影响因子：
25.4
作者：
Brewer, Noel T.;Chapman, Gretchen B.;Kempe, Allison
通讯作者：
Kempe, Allison
影响因子：
9.7
作者：
Chang, Angela Y.;Riumallo-Herl, Carlos;Verguet, Stephane
通讯作者：
Verguet, Stephane
DOI：
10.1016/s1470-2045(21)00453-8
发表时间：
2021-11
期刊：
The Lancet. Oncology
影响因子：
--
作者：
Basu P;Malvi SG;Joshi S;Bhatla N;Muwonge R;Lucas E;Verma Y;Esmy PO;Poli URR;Shah A;Zomawia E;Pimple S;Jayant K;Hingmire S;Chiwate A;Divate U;Vashist S;Mishra G;Jadhav R;Siddiqi M;Sankaran S;Prabhu PR;Kannan TPRA;Varghese R;Shastri SS;Anantharaman D;Gheit T;Tommasino M;Sauvaget C;Pillai MR;Sankaranarayanan R
通讯作者：
Sankaranarayanan R
DOI：
10.1007/s12639-021-01387-w
发表时间：
2021-06
期刊：
Journal of parasitic diseases : official organ of the Indian Society for Parasitology
影响因子：
--
作者：
Al-Naseri A;Al-Absi S;El Ridi R;Mahana N
通讯作者：
Mahana N
DOI：
10.1056/nejmoa2031499
发表时间：
2021-03-25
期刊：
The New England journal of medicine
影响因子：
--
作者：
Gray GE;Bekker LG;Laher F;Malahleha M;Allen M;Moodie Z;Grunenberg N;Huang Y;Grove D;Prigmore B;Kee JJ;Benkeser D;Hural J;Innes C;Lazarus E;Meintjes G;Naicker N;Kalonji D;Nchabeleng M;Sebe M;Singh N;Kotze P;Kassim S;Dubula T;Naicker V;Brumskine W;Ncayiya CN;Ward AM;Garrett N;Kistnasami G;Gaffoor Z;Selepe P;Makhoba PB;Mathebula MP;Mda P;Adonis T;Mapetla KS;Modibedi B;Philip T;Kobane G;Bentley C;Ramirez S;Takuva S;Jones M;Sikhosana M;Atujuna M;Andrasik M;Hejazi NS;Puren A;Wiesner L;Phogat S;Diaz Granados C;Koutsoukos M;Van Der Meeren O;Barnett SW;Kanesa-Thasan N;Kublin JG;McElrath MJ;Gilbert PB;Janes H;Corey L;HVTN 702 Study Team
通讯作者：
HVTN 702 Study Team