A model of lung parenchyma stress relaxation using fractional viscoelasticity.

A model of lung parenchyma stress relaxation using fractional viscoelasticity.
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使用分数粘弹性的肺实质释放模型。

DOI:
10.1016/j.medengphy.2015.05.003
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发表时间:
2015-08
影响因子:
2.2
通讯作者:
Royston TJ
Royston TJ
中科院分区:
工程技术3区
文献类型:
--
作者:
Dai Z;Peng Y;Mansy HA;Sandler RH;Royston TJ

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一些肺部疾病和损伤被认为与肺的粘弹性变化有关。因此,更好地理解肺的粘弹性模型可以为肺病理和创伤的进展提供新的视角。在目前的研究中,应力松弛测量被用来量化猪肺的松弛行为。结果揭示了某些趋势,包括最初的急剧衰减,然后是缓慢的渐近松弛,这将更好地用幂定律来描述,而不是指数衰减。用分数阶标准线性固体(FSLS)和两种整数阶粘弹性模型--标准线性固体(SLS)和广义麦克斯韦(GM)模型对应力松弛曲线进行了拟合,发现分数阶标准线性固体(FSLS)对应力松弛曲线的拟合效果较好。结果表明,分数阶粘弹性模型具有非局域性、多尺度特性,且表现出幂函数行为,能更好地反映肺实质的粘弹性行为。
Some pulmonary diseases and injuries are believed to correlate with lung viscoelasticity changes. Hence, a better understanding of lung viscoelastic models could provide new perspectives on the progression of lung pathology and trauma. In the presented study, stress relaxation measurements were performed to quantify relaxation behavior of pig lungs. Results have uncovered certain trends, including an initial steep decay followed by a slow asymptotic relaxation, which would be better described by a power law than exponential decay. The fractional standard linear solid (FSLS) and two integer order viscoelastic models – standard linear solid (SLS) and generalized Maxwell (GM) – were used to fit the stress relaxation curves; the FSLS was found to be a better fit. It is suggested that fractional order viscoelastic models, which have nonlocal, multi-scale attributes and exhibit power law behavior, better capture the lung parenchyma viscoelastic behavior.
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