Translational Informatics Connects Real-World Information to Knowledge in an Increasingly Data-Driven World.

Translational Informatics Connects Real-World Information to Knowledge in an Increasingly Data-Driven World.
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DOI:
10.1002/cpt.1719
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发表时间:
2020-04
影响因子:
6.7
通讯作者:
Tuteja S
Tuteja S
中科院分区:
医学2区
文献类型:
--
作者:
McDonough CW;Breitenstein MK;Shahin M;Empey PE;Freimuth RR;Li L;Liebman M;Tuteja S

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临床药理学社区站在一场数据赋能革命的尖端,从现实世界的数据源中确定的健康数据人工制品,包括电子健康记录(EHR)、患者可穿戴设备、基因组学和其他组学,拥有重要的机会来告知我们对患者结果的理解。在更大、更具代表性的人群中,推进我们对选定患者为什么对某些疗法没有反应的分子理解的机会将使未来的药物发现和研究变得更加容易。
The clinical pharmacology community stands on the cusp of a data-empowered revolution, where health data artifacts ascertained from real-world data sources, including electronic health records (EHRs), patient wearables, genomics and other ‘omics, hold momentous opportunity to inform our understanding of patient outcomes. The opportunity to advance our molecular understanding of why select patients do not respond to certain therapies in larger more representative populations will empower future drug discovery and facilitate research.
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