Prevalence and burden of gait disorders in elderly men and women aged 60-97 years: a population-based study.
Prevalence and burden of gait disorders in elderly men and women aged 60-97 years: a population-based study.
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DOI：
10.1371/journal.pone.0069627
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发表时间：
2013
期刊：
影响因子：
3.7
通讯作者：
Seppi K
中科院分区：
文献类型：
--
作者：
Mahlknecht P;Kiechl S;Bloem BR;Willeit J;Scherfler C;Gasperi A;Rungger G;Poewe W;Seppi K
虽然步态障碍在老年人中很常见，但这些疾病在一般社区中的患病率和总体负担尚未明确。在一项基于人群的Bruneck研究队列的横断面调查中，488名年龄在60-97岁的社区老年人接受了全面的神经系统评估，包括标准化步态评估。根据公认的方案对步态障碍进行分类，并探讨其与福尔斯、神经心理学指标和生活质量的关系。总体而言，32.2%（95%置信区间[CI] 28.2%-36.4%）的参与者出现步态受损。患病率随年龄增长而增加（p<0.001），但80岁或以上的受试者中仍有38.3%（95%CI 30.1%-47.3%）的步态保持正常。共有24.0%（95%CI 20.4%-28.0%）的患者表现为神经性步态障碍，17.4%（14.3%-21.0%）的患者表现为非神经性步态问题，9.2%（6.9%-12.1%）的患者表现为两者兼而有之。虽然神经性步态障碍与性别无关，但非神经性步态障碍在女性中更常见（p = 0.012）。 在神经性步态障碍组中，69.2%（95%CI 60.3%-76.9%）的患者有单一的步态障碍，30.8%（23.1%-39.7%）的患者有多种神经性步态障碍。步态障碍对定量步态测量有显著的负面影响，但只有神经性步态障碍与复发性福尔斯相关（单一神经性步态障碍的比值比为3.3; 95%CI 1.4-7.5; p = 0.005;多发性神经性步态障碍的比值比为7.1; 2.7-18.7; p<0.001）。 最后，我们检测到步态障碍，特别是神经步态障碍，与抑郁情绪，认知功能障碍和生活质量受损的显着关联。步态障碍在一般老年人群中很常见，并与活动能力降低有关。神经性步态障碍尤其与复发性福尔斯、认知功能低下、情绪抑郁和生活质量下降相关。
Although gait disorders are common in the elderly, the prevalence and overall burden of these disorders in the general community is not well defined. In a cross-sectional investigation of the population-based Bruneck Study cohort, 488 community-residing elderly aged 60–97 years underwent a thorough neurological assessment including a standardized gait evaluation. Gait disorders were classified according to an accepted scheme and their associations to falls, neuropsychological measures, and quality of life were explored. Overall, 32.2% (95% confidence interval [CI] 28.2%–36.4%) of participants presented with impaired gait. Prevalence increased with age (p<0.001), but 38.3% (95%CI 30.1%–47.3%) of the subjects aged 80 years or older still had a normally preserved gait. A total of 24.0% (95%CI 20.4%–28.0%) manifested neurological gait disorders, 17.4% (14.3%–21.0%) non-neurological gait problems, and 9.2% (6.9%–12.1%) a combination of both. While there was no association of neurological gait disorders with gender, non-neurological gait disorders were more frequent in women (p = 0.012). Within the group of neurological gait disorders 69.2% (95%CI 60.3%–76.9%) had a single distinct entity and 30.8% (23.1%–39.7%) had multiple neurological causes for gait impairment. Gait disorders had a significant negative impact on quantitative gait measures, but only neurological gait disorders were associated with recurrent falls (odds ratio 3.3; 95%CI 1.4–7.5; p = 0.005 for single and 7.1; 2.7–18.7; p<0.001 for multiple neurological gait disorders). Finally, we detected a significant association of gait disorders, in particular neurological gait disorders, with depressed mood, cognitive dysfunction, and compromised quality of life. Gait disorders are common in the general elderly population and are associated with reduced mobility. Neurological gait disorders in particular are associated with recurrent falls, lower cognitive function, depressed mood, and diminished quality of life.
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DOI：
10.1111/j.1532-5415.1986.tb05480.x
发表时间：
1986-02-01
影响因子：
6.3
作者：
TINETTI, ME
通讯作者：
TINETTI, ME
影响因子：
1.8
作者：
Agresti, A;Coull, BA
通讯作者：
Coull, BA
影响因子：
--
作者：
ODENHEIMER, G;FUNKENSTEIN, HH;ALBERT, M
通讯作者：
ALBERT, M
影响因子：
4.9
作者：
Schwaiger, J.;Kiechl, S.;Willeit, J.
通讯作者：
Willeit, J.
DOI：
10.1111/j.1532-5415.1991.tb01616.x
发表时间：
1991-02-01
影响因子：
6.3
作者：
PODSIADLO, D;RICHARDSON, S
通讯作者：
RICHARDSON, S