Peripapillary optical coherence tomography as an alternative to fluorescein angiography for monitoring Behcet's retinal vasculitis.
Peripapillary optical coherence tomography as an alternative to fluorescein angiography for monitoring Behcet's retinal vasculitis.
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DOI：
10.1038/s41598-021-99485-5
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发表时间：
2021-10-08
影响因子：
4.6
通讯作者：
Ebrahimiadib N
中科院分区：
文献类型：
--
作者：
Zarei M;Pesarakli H;Yaseri M;Etesali H;Ebrahimiadib N
目的探讨黄斑中心亚区厚度(CSMT)、视网膜乳头周围厚度(PRT)、乳头周围神经纤维层厚度(PNFLT)等OCT参数与荧光素血管成像(FA)在评价白塞氏视网膜血管炎炎症活动性中的相关性。在该病例系列中，同时进行了FA和OCT检查。为足总设计了一套评分系统。测量了直径3.4 mm圆内的PNFlt和直径1 mm至2.2 mm圆之间以及直径2.2 mm至3.45 mm圆之间的甜甜圈形状区域的PRT。分析了FA与OCT参数的相关性。共复习了15例28只眼的105组FA。女性4例(26.6%)，平均年龄31.6 ± 8.49岁。CSMT、PRT2.2、PRT3.45和PNFLT每增加一微米，分别导致0.018(95%CI 0.008-0.027，P <； 0.001，r = 0.413)、0.053(95%CI 0.035-0.070，P <； 0.001，r = 0.443)、0.086%(95%CI 0.065-0.108，P <； 0.001，r = 0.707)和0.185(95%CI 0.152-to 0.218，P <； 0.001，r = 0.850)单位。与血管造影炎性活动显著相关的参数有CSMT、PRT2.2、PRT3.45和RNFLT。相关性最强的PRT3.45和PNFLT可被认为是监测白塞氏视网膜血管炎的定量非侵入性替代FA。
To study the correlation of OCT parameters including central subfield macular thickness (CSMT), peripapillary retinal thickness (PRT), and peripapillary retinal nerve fiber layer thickness (PNFLT) with fluorescein angiography (FA) in evaluation of inflammatory activity in Behcet’s retinal vasculitis. In this case-series, concurrent FA and OCT were performed. A scoring system was devised for FA. PNFLT in 3.4-mm-diameter circle as well as PRT in doughnut shaped regions between the 1-mm- and 2.2-mm-diameter and between the 2.2-mm- and 3.45-mm-diameter circles was measured. The correlation of FA and OCT parameters was analyzed. A total of 105 sets of FA from 28 eyes (15 patients) were reviewed. Four (26.6%) were female and mean age was 31.6 ± 8.49 years. Each micron increase in CSMT, PRT2.2, PRT3.45, and PNFLT, caused a rise of 0.018 (95% CI 0.008–0.027, P < 0.001, r = 0.413), 0.053 (95% CI 0.035–0.070, P < 0.001, r = 0.443), 0.086 (95% CI 0.065–0.108, P < 0.001, r = 0.707), and 0.185 (95% CI 0.152–to 0.218, P < 0.001, r = 0.850) unit in FA score, respectively. Parameters having significant correlation with angiographic inflammatory activity, were CSMT, PRT2.2, PRT3.45 and RNFLT. Those with the strongest correlation, PRT3.45 and PNFLT, may be considered as quantitative non-invasive alternatives to FA for monitoring Behcet’s retinal vasculitis.
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影响因子：
1.6
作者：
Tugal-Tutkun, Ilknur;Herbort, Carl P.;Khairallah, Moncef
通讯作者：
Khairallah, Moncef
影响因子：
4.2
作者：
Monnet, Dominique;Levinson, Ralph D.;Brezin, Antoine P.
通讯作者：
Brezin, Antoine P.
影响因子：
2.5
作者：
Hittner, JB;May, K;Silver, NC
通讯作者：
Silver, NC
影响因子：
3.3
作者：
Yalcindag, F. Nilufer;Ozdal, Pinar C.;Tugal-Tutkun, Ilknur
通讯作者：
Tugal-Tutkun, Ilknur
影响因子：
1.7
作者：
Bazvand, Fatemeh;Zarei, Mohammad;Modjtahedi, Bobeck S.
通讯作者：
Modjtahedi, Bobeck S.