Unraveling mosquito metabolism with mass spectrometry-based metabolomics.

Unraveling mosquito metabolism with mass spectrometry-based metabolomics.
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DOI:
10.1016/j.pt.2021.03.010
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发表时间:
2021-08
影响因子:
9.6
通讯作者:
Scaraffia PY
Scaraffia PY
中科院分区:
医学1区
文献类型:
--
作者:
Horvath TD;Dagan S;Scaraffia PY

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Nearly half a million people die annually due to mosquito-borne diseases. Despite aggressive mosquito population-control efforts, current strategies are limited in their ability to control these vectors. A better understanding of mosquito metabolism through modern approaches can contribute to the discovery of novel metabolic targets and/or regulators and lead to the development of better mosquito-control strategies. Currently, cutting-edge technologies such as gas or liquid chromatography–mass spectrometry-based metabolomics are considered ‘mature technologies’ in many life-science disciplines but are still an emerging area of research in medical entomology. This review primarily discusses recent developments and progress in the application of mass spectrometry-based metabolomics to answer multiple biological questions related to mosquito metabolism.
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