Parent Attitudes Towards Childhood Vaccines After the Onset of SARS-CoV-2 in the United States.

Parent Attitudes Towards Childhood Vaccines After the Onset of SARS-CoV-2 in the United States.
复制标题

DOI:
10.1016/j.acap.2022.06.014
复制
发表时间:
2022-11
影响因子:
3.1
通讯作者:
O'Leary, Sean
O'Leary, Sean
中科院分区:
医学3区
文献类型:
--
作者:
Opel, Douglas J.;Furniss, Anna;Zhou, Chuan;Rice, John D.;Spielvogle, Heather;Spina, Christine;Perreira, Cathryn;Giang, Jessica;Dundas, Nicolas;Dempsey, Amanda;Pahud, Barbara;Robinson, Jeffrey;O'Leary, Sean

文献摘要

参考文献

被引文献

相似文献

了解一种新的传染病流行对家长对儿童疫苗的普遍态度的影响。我们利用华盛顿州和科罗拉多州参与2019年9月27日开始的更大规模试验的婴儿父母的横断面调查数据进行了一项自然实验。在注册时,家长们完成了简短版本的家长对儿童疫苗的态度(PACV-SF),这是一个有效的调查,得分从0到4,分数越高,代表着更多的负面态度。暴露变量为美国SARS-CoV-2大流行开始,前阶段定义为2019年9月27日至2020年2月28日,后阶段定义为2020年4月1日至2020年12月10日,后阶段进一步分为近阶段(2020年4月1日至2020年7月31日)和远期(2020年8月1日至2020年12月10日)。结果变量是父母对儿童疫苗的负面态度,定义为PACV-SF的≥2分。我们使用对数二项回归估计暴露后(与暴露前)结果的概率,并根据人口统计混杂变量调整了广义估计方程。在4562名家长中,在SARS-CoV-2发病后立即(与发病前相比),负面态度的风险较低(调整后的风险比[ARR]=40.58;95%可信区间[CI],0.36,0.94;P=4.027),但到2020年8-12月,平均负面态度的比率比2020年4-7月期间高35%(ARR:1.35;95%CI:1.13,1.61;P=0.0009)。在SARS-CoV-2发病后立即观察到的普遍负面疫苗态度的降低风险迅速减弱。
To understand the influence of a novel infectious disease epidemic on parent general attitudes about childhood vaccines. We conducted a natural experiment utilizing cross-sectional survey data from parents of infants in Washington and Colorado participating in a larger trial that began on September 27, 2019. At enrollment, parents completed the short version of the Parental Attitudes about Childhood Vaccines (PACV-SF), a validated survey scored from 0 to 4, with higher scores representing more negative attitudes. The exposure variable was onset of the SARS-CoV-2 pandemic in the United States, with the before-period defined as September 27, 2019 to February 28, 2020 and the after-period defined as April 1, 2020—December 10, 2020, with the after-period further separated into proximate (April 1, 2020–July 31, 2020) and distant periods (August 1, 2020–December 10, 2020). The outcome variable was parent negative attitudes about childhood vaccines, defined as a score of ≥2 on the PACV-SF. We estimated the probability of the outcome after (vs before) the exposure using log-binomial regression with generalized estimating equations adjusted for demographic confounding variables. Among 4562 parents, the risk of negative attitudes was lower immediately after (vs before) SARS-CoV-2 onset (adjusted risk ratio [aRR] = 0.58; 95% confidence interval [CI], 0.36, 0.94; P = .027), but by August–December 2020, the average rate of negative attitudes was 35% higher than during April–July 2020 (aRR: 1.35; 95% CI: 1.13, 1.61; P = .0009). A reduced risk of negative general vaccine attitudes observed immediately after SARS-CoV-2 onset was quickly attenuated.
DOI: 10.15585/mmwr.mm6918e2
发表时间: 2020-05-08
期刊: MMWR. Morbidity and mortality weekly report
影响因子: --
作者:
Schuchat A;CDC COVID-19 Response Team
通讯作者: CDC COVID-19 Response Team
DOI: 10.4161/hv.7.4.14120
发表时间: 2011-04-01
期刊: HUMAN VACCINES
影响因子: --
作者:
Opel, Douglas J.;Mangione-Smith, Rita;Martin, Diane P.
通讯作者: Martin, Diane P.
DOI: 10.1177/1529100618760521
发表时间: 2017-12-01
影响因子: 25.4
作者:
Brewer, Noel T.;Chapman, Gretchen B.;Kempe, Allison
通讯作者: Kempe, Allison
DOI: 10.1080/21645515.2018.1463943
发表时间: 2018-01-01
影响因子: 4.8
作者:
Napolitano, Francesco;D'Alessandro, Alessia;Angelillo, Italo Francesco
通讯作者: Angelillo, Italo Francesco
DOI: 10.1016/j.vaccine.2016.10.048
发表时间: 2016-12-07
期刊: VACCINE
影响因子: 5.5
作者:
Cataldi, Jessica R.;Dempsey, Amanda F.;O'Leary, Sean T.
通讯作者: O'Leary, Sean T.