Entering adolescence: resistance to peer influence, risky behavior, and neural changes in emotion reactivity.

Entering adolescence: resistance to peer influence, risky behavior, and neural changes in emotion reactivity.
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进入青春期:对同伴影响,风险行为和情绪反应性的神经变化的抵抗力。

DOI:
10.1016/j.neuron.2011.02.019
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发表时间:
2011-03-10
期刊:
影响因子:
16.2
通讯作者:
Dapretto M
Dapretto M
中科院分区:
医学1区
文献类型:
--
作者:
Pfeifer JH;Masten CL;Moore WE 3rd;Oswald TM;Mazziotta JC;Iacoboni M;Dapretto M

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青春期通常被描述为一个对情绪反应强烈的时期,伴随着调节能力的降低,这一组合被认为有助于青春期的冒险行为和对同伴影响的敏感性。然而,没有纵向研究明确地将这些行为变化与潜在的神经发育联系起来。在这里,38名神经典型的参与者在从儿童晚期(10年)到青春期早期(13年)的过渡期间接受了两次fMRI会议。情感面部显示的反应表现出的腹侧纹状体(VS),腹内侧PFC,杏仁核,颞极的一般和情绪特异性的变化相结合。此外,VS活动的增加与对同伴影响和危险行为的敏感性降低相关。VS和杏仁核反应也显着更负耦合在青春期早期比在童年后期,而处理悲伤和快乐与中性的面孔。总之,这些结果表明,VS反应观看情绪可能发挥调节作用,是至关重要的青少年的人际功能。
Adolescence is often described as a period of heightened reactivity to emotions paired with reduced regulatory capacities, a combination suggested to contribute to risk-taking and susceptibility to peer influence during puberty. However, no longitudinal research has definitively linked these behavioral changes to underlying neural development. Here, 38 neurotypical participants underwent two fMRI sessions across the transition from late childhood (10 years) to early adolescence (13 years). Responses to affective facial displays exhibited a combination of general and emotion-specific changes in ventral striatum (VS), ventromedial PFC, amygdala, and temporal pole. Furthermore, VS activity increases correlated with decreases in susceptibility to peer influence and risky behavior. VS and amygdala responses were also significantly more negatively coupled in early adolescence than in late childhood while processing sad and happy versus neutral faces. Together, these results suggest that VS responses to viewing emotions may play a regulatory role that is critical to adolescent interpersonal functioning.
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发表时间: 2009-02-01
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影响因子: 5.7
作者:
Levita L;Hare TA;Voss HU;Glover G;Ballon DJ;Casey BJ
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