The bivalent side of the nucleus accumbens.

The bivalent side of the nucleus accumbens.
复制标题

DOI:
10.1016/j.neuroimage.2008.09.039
复制
发表时间:
2009-02-01
期刊:
影响因子:
5.7
通讯作者:
Casey BJ
Casey BJ
中科院分区:
医学1区
文献类型:
--
作者:
Levita L;Hare TA;Voss HU;Glover G;Ballon DJ;Casey BJ

文献摘要

参考文献

被引文献

相似文献

越来越多的证据表明,伏隔核(NAcc)参与激励奖励过程以及对条件和非条件厌恶刺激的适应性反应。然而,有人认为,NAcc 对厌恶刺激的激活可能是其终止(即缓解)的奖励效应的结果。为了解决这个问题,我们使用功能磁共振成像来描绘在没有学习或运动反应的情况下,大脑对不愉快和愉快的听觉刺激的开始和抵消的反应。在愉快和不愉快的刺激出现时,NAcc 活性都会增加。我们的结果支持 NAcc 功能的扩展二价观点,并呼吁扩展仅关注奖励的当前 NAcc 功能模型。
An increasing body of evidence suggests that the nucleus accumbens (NAcc) is engaged in both incentive reward processes and in adaptive responses to conditioned and unconditioned aversive stimuli. Yet, it has been argued that NAcc activation to aversive stimuli may be a consequence of the rewarding effects of their termination, i.e., relief. To address this question we used fMRI to delineate brain response to the onset and offset of unpleasant and pleasant auditory stimuli in the absence of learning or motor response. Increased NAcc activity was seen for the onset of both pleasant and unpleasant stimuli. Our results support the expanded bivalent view of NAcc function and call for expansion of current models of NAcc function that are solely focused on reward.
DOI: 10.1523/jneurosci.21-06-02159.2001
发表时间: 2001-03-15
影响因子: 5.3
作者:
Bourgeais, L;Monconduit, L;Bernard, JF
通讯作者: Bernard, JF
DOI: 10.1016/s0896-6273(00)80219-6
发表时间: 1996-11-01
期刊: NEURON
影响因子: 16.2
作者:
Breiter, HC;Etcoff, NL;Rosen, BR
通讯作者: Rosen, BR
DOI: 10.1002/mrm.20016
发表时间: 2004-04-01
影响因子: 3.3
作者:
Glover, GH;Thomason, ME
通讯作者: Thomason, ME
DOI: 10.1523/jneurosci.4961-07.2008
发表时间: 2008-07-09
影响因子: 5.3
作者:
Faure, Alexis;Reynolds, Sheila M.;Richard, Jocelyn M.;Berridge, Kent C.
通讯作者: Berridge, Kent C.
DOI: 10.1016/s0165-0173(99)00049-1
发表时间: 2000-03-01
影响因子: --
作者:
Grace, AA
通讯作者: Grace, AA