Children's binge eating and development of metabolic syndrome.

Children's binge eating and development of metabolic syndrome.
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DOI:
10.1038/ijo.2011.259
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发表时间:
2012-07
影响因子:
4.9
通讯作者:
Yanovski, J. A.
Yanovski, J. A.
中科院分区:
医学2区
文献类型:
--
作者:
Tanofsky-Kraff, M.;Shomaker, L. B.;Stern, E. A.;Miller, R.;Sebring, N.;DellaValle, D.;Yanovski, S. Z.;Hubbard, V. S.;Yanovski, J. A.

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Binge eating predisposes children to excessive weight gain. However, it is unknown if pediatric binge eating predicts other obesity-associated adverse health outcomes. The objective of this study was to investigate the relationship between binge eating and metabolic syndrome (MetS) in children. Children 5–12 y at high risk for adult obesity, either because they were overweight/obese when first examined or because their parents were overweight/obese, were recruited from Washington, DC and its suburbs. Children completed a questionnaire assessment of binge eating at baseline and underwent measurements of MetS components at baseline and at a follow-up visit approximately 5 years later. Magnetic resonance imaging was used to measure visceral adipose tissue (VAT) in a subset. One hundred eighty children were studied between July, 1996 and August, 2010. Baseline self-reported binge eating presence was associated with a 5.33 greater odds of having MetS at follow-up (95% CI: 1.47, 19.27, p = 0.01). The association between binge eating and BMI only partially explained changes in MetS components: baseline binge eating predicted higher follow-up triglycerides, even after accounting for baseline triglycerides, baseline BMI, BMI change, sex, race, baseline age, and time in study (p = 0.05). Also, adjusting for baseline VAT and demographics, baseline binge eating predicted greater follow-up L2-3 VAT (p = 0.01). Children’s reports of binge eating predicted development of MetS, worsening triglycerides, and increased VAT. The excessive weight gain associated with children’s binge eating partly explained its adverse metabolic health outcomes. Reported binge eating may represent an early behavioral marker upon which to focus interventions for obesity and MetS.
DOI: 10.1196/annals.1410.035
发表时间: 2008-12
影响因子: 5.2
作者:
Kuo LE;Czarnecka M;Kitlinska JB;Tilan JU;Kvetnanský R;Zukowska Z
通讯作者: Zukowska Z
DOI: 10.1210/jc.2008-2665
发表时间: 2009-12-01
影响因子: 5.8
作者:
Gustafson, Jennifer K.;Yanoff, Lisa B.;Yanovski, Jack A.
通讯作者: Yanovski, Jack A.
DOI: 10.1037//1082-989x.7.2.147
发表时间: 2002-06-01
影响因子: 7
作者:
Schafer, JL;Graham, JW
通讯作者: Graham, JW
DOI: 10.1203/00006450-198003000-00004
发表时间: 1980-01-01
期刊: PEDIATRIC RESEARCH
影响因子: 3.6
作者:
CHRISTENSEN, B;GLUECK, C;RIFKIND, B
通讯作者: RIFKIND, B
DOI: 10.1016/j.jpeds.2007.09.010
发表时间: 2008-02-01
影响因子: 5.1
作者:
Morrison, John A.;Friedman, Lisa Aronson;Glueck, Charles J.
通讯作者: Glueck, Charles J.