Non-coding RNA in Ovarian Development and Disease.
Non-coding RNA in Ovarian Development and Disease.
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DOI：
10.1007/978-94-017-7417-8_5
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发表时间：
2016
影响因子：
--
通讯作者：
Christenson LK
中科院分区：
文献类型：
--
作者：
Fitzgerald JB;George J;Christenson LK
The ovary’s primary function is to produce the mature female gamete, the oocyte that, following fertilization, can develop into an embryo, implant within the uterus and ultimately allow the mother’s genetic material to be passed along to subsequent generations. In addition to supporting the generation of the oocyte, the ovary and specific ephemeral tissues within it, follicles and corpora lutea, produce steroids that regulate all aspects of the reproductive system, including the hypothalamic/pituitary axis, the reproductive tract (uterus, oviduct, cervix), secondary sex characteristics all of which are also essential for pregnancy and subsequent nurturing of the offspring. To accomplish these critical roles, ovarian development and function are tightly regulated by a number of exogenous (hypothalamic/pituitary) and endogenous (intraovarian) hormones. Within ovarian cells, intricate signalling cascades and transcriptional and post-transcriptional gene regulatory networks respond to these hormonal influences to provide the exquisite control over all of the temporal and spatial events that must be synchronized to allow this organ to successfully complete its function. This book chapter will focus specifically on the role of non-coding RNAs, their identification and described functional roles within the ovary with respect to normal function and their possible involvement in diseases, which involve the ovary.
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影响因子：
3.6
作者：
Carletti, Martha Z.;Fiedler, Stephanie D.;Christenson, Lane K.
通讯作者：
Christenson, Lane K.
影响因子：
3.6
作者：
Fiedler, Stephanie D.;Carletti, Martha Z.;Christenson, Lane K.
通讯作者：
Christenson, Lane K.
影响因子：
2.1
作者：
ARIEL, I;LUSTIG, O;HOCHBERG, A
通讯作者：
HOCHBERG, A
microRNA在卵巢癌的肿瘤发生中的作用。
影响因子：
4.7
作者：
Di Leva G;Croce CM
通讯作者：
Croce CM
miRNA-93抑制GLUT4，并在多囊卵巢综合征患者和具有胰岛素抵抗的女性的脂肪组织中过表达。
影响因子：
7.7
作者：
Chen YH;Heneidi S;Lee JM;Layman LC;Stepp DW;Gamboa GM;Chen BS;Chazenbalk G;Azziz R
通讯作者：
Azziz R