Maternal pre-pregnancy weight and gestational weight gain and their association with birthweight with a focus on racial differences.

Maternal pre-pregnancy weight and gestational weight gain and their association with birthweight with a focus on racial differences.
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DOI:
10.1007/s10995-012-0950-x
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发表时间:
2013-01
影响因子:
2.3
通讯作者:
Korte JE
Korte JE
中科院分区:
医学4区
文献类型:
--
作者:
Hunt KJ;Alanis MC;Johnson ER;Mayorga ME;Korte JE

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研究母亲孕前体重指数 (BMI) 和妊娠期体重增加 (GWG) 之间的相互作用及其与出生体重的关系,重点关注种族差异。我们使用南卡罗来纳州居民母亲的活单胎出生证明数据进行横断面研究,这些母亲自我报告自己的种族为非西班牙裔白人(NHW,n=140,128)或非西班牙裔黑人(NHB,n=82,492),并在 2004 年至 2008 年期间在妊娠 34-44 周分娩。线性回归用于检查我们的暴露(即种族、BMI 和 GWG)与结果出生体重之间的关系。根据 2009 年医学研究所指南,NHW 女性中 GWG 充足、不足和过量的发生率分别为 27.1%、24.2% 和 48.7%,NHB 女性中分别为 24.2%、34.8% 和 41.0%。调整婴儿性别、胎龄、产妇年龄、烟草使用、教育、产前护理和医疗补助后,在 BMI 为 30 kg/m2 的产妇中,过量和充足 GWG 之间的出生体重差异在 NHW 女性中为 118 克(95% CI:109, 127),在 NHB 女性中为 101 克(95% CI:91, 111)。此外,在 NHW [OR=0.64 (95% CI 0.61, 0.67)] 和 NHB 女性 [OR=0.68 (95% CI: 0.65, 0.72)] 中,过量与充足的 GWG 可以提供类似的保护,避免生出小于胎龄儿。我们报告称,在 NHW 和 NHB 女性中,不同孕产妇 BMI 级别的 GWG 过高与较高的婴儿出生体重之间存在密切关联。鉴于体重增加过多的现象非常普遍,即使出生体重的小幅增加也可能对人口水平产生相当大的影响。
To examine the interaction between maternal pre-pregnancy body mass index (BMI) and gestational weight gain (GWG) and their association with birthweight, with a focus on racial differences. We used birth certificate data from live singleton births of South Carolina resident mothers, who self-reported their race as non-Hispanic white (NHW, n=140,128) or non-Hispanic black (NHB, n=82,492) and who delivered at 34–44 weeks of gestation between 2004–2008 to conduct a cross-sectional study. Linear regression was used to examine the relationship between our exposures (i.e., race, BMI and GWG) and our outcome birthweight. Based on 2009 Institute of Medicine guidelines, the prevalence of adequate, inadequate and excessive GWG was 27.1%, 24.2% and 48.7%, respectively, in NHW women and 24.2%, 34.8% and 41.0%, respectively, in NHB women. Adjusting for infant sex, gestational age, maternal age, tobacco use, education, prenatal care, and Medicaid, the difference in birthweight between excessive and adequate GWG at a maternal BMI of 30 kg/m2 was 118g (95% CI: 109, 127) in NHW women and 101g (95% CI: 91, 111) in NHB women. Moreover, excessive versus adequate GWG conveyed similar protection from having a small for gestational age infant in NHW [OR=0.64 (95% CI 0.61, 0.67)] and NHB women [OR=0.68 (95% CI: 0.65, 0.72)]. We report a strong association between excessive GWG and higher infant birthweight across maternal BMI classes in NHW and NHB women. Given the high prevalence of excessive GWG even a small increase in birthweight may have considerable implications at the population level.
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