Contribution of platelets to tumour metastasis.
Contribution of platelets to tumour metastasis.
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DOI:
10.1038/nrc3004
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发表时间:
2011-03
期刊:
影响因子:
--
通讯作者:
Felding-Habermann B
中科院分区:
文献类型:
--
作者:
Gay LJ;Felding-Habermann B
Extensive experimental evidence shows that platelets support tumor metastasis. The activation of platelets and the coagulation system play a critical role in the progression of cancer. Within the circulatory system, platelets guard tumor cells from immune elimination and promote their arrest at the endothelium, supporting the establishment of secondaruy lesions. These contributions of platelets to tumor cell survival and spread recognize platelets as a new avenue for therapy.
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