Micronutrients in COVID-19 Positive Pregnancies.
Micronutrients in COVID-19 Positive Pregnancies.
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DOI：
10.7759/cureus.10609
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发表时间：
2020-09-23
期刊：
影响因子：
--
通讯作者：
Polat İ
中科院分区：
文献类型：
--
作者：
Yalcin Bahat P;Aldikactioglu Talmac M;Bestel A;Topbas Selcuki NF;Aydın Z;Polat İ
孕妇被认为是COVID-19的高危人群。因此，研究治疗和预防COVID-19阳性妊娠的方法非常重要。这项研究的目的是测量COVID-19阳性孕妇的血清25（OH）D，维生素B12和锌水平，以评估这些微量营养素在治疗和预防中的作用。本研究共纳入了44名在三级诊所住院和治疗的COVID-19阳性孕妇。血清25（OH）D平均值为9.70 ± 59.14，血清锌平均值为62.58 ± 2.63，血清维生素B12平均值为295.55 ± 302.48。所有这些变量均显著低于可接受的临界值（p < 0.001）。这些低值可能导致了他们的免疫反应缺陷，从而使这些患者容易感染COVID-19。在大流行期间补充微量营养素可能有利于怀孕期间的预防。
Pregnant women are considered among the high-risk population for COVID-19. Therefore, research for methods of treatment and prevention of COVID-19 positive pregnancies carries an importance. The aim of this study was to measure serum 25(OH)D, vitamin B12, and zinc levels in COVID-19 positive pregnant women to evaluate the role of these micronutrients in treatment and prevention. A total of 44 COVID-19 positive pregnant women who were hospitalized and treated at a tertiary clinic were included in this study. The mean serum 25(OH)D level was measured to be 9.70 ± 59.14. The mean serum zinc level was 62.58 ± 2.63, and the mean serum vitamin B12 level was 295.55 ± 302.48. All these variables were significantly lower than the accepted cut-off values (p < 0.001). These low values might have contributed to a deficiency in their immune response and thus made these patients susceptible to COVID-19 infection. Supplementation of micronutrients during the pandemic could be beneficial during pregnancy for prevention.
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