The pentatricopeptide repeat-SMR protein ATP4 promotes translation of the chloroplast atpB/E mRNA.
The pentatricopeptide repeat-SMR protein ATP4 promotes translation of the chloroplast atpB/E mRNA.
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五肽重复 SMR 蛋白 ATP4 促进叶绿体 atpB/E mRNA 的翻译
DOI:
10.1111/j.1365-313x.2012.05081.x
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发表时间:
2012
期刊:
影响因子:
--
通讯作者:
Schmitz-Linneweber C
中科院分区:
文献类型:
--
作者:
Zoschke R;Kroeger T;Belcher S;Schöttler MA;Barkan A;Schmitz-Linneweber C
The regulation of chloroplast translation by nuclear gene products makes a major contribution to the control of chloroplast gene expression, but the underlying mechanisms are poorly understood. We describe a pentatricopeptide repeat (PPR) protein in maize, ATP4, that is necessary for translation of the chloroplastatpBopen reading frame. We demonstrate that ATP4 associatesin vivowith sequences near the 5′ end of the unusually long 5′ UTR of theatpB/EmRNA, that it facilitates ribosome association with this mRNA, and that it is required for accumulation and activity of the chloroplast ATP synthase. ATP4 is multifunctional, in that it also enhancesatpAtranslation and is required for accumulation of specific processedatpFandpsaJtranscripts. ATP4 belongs to a sub‐class of PPR proteins that include a small MutS‐related (SMR) domain. SMR domains had previously been associated primarily with DNA‐related functions, but our findings imply that at least some PPR‐SMR proteins can act on RNA. ATP4 is orthologous to the Arabidopsis protein SVR7, but the phenotypes ofatp4andsvr7mutants suggest that the functions of these orthologs have not been strictly conserved.
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影响因子:
11.4
作者:
Yuichiro Takahashi;M. Goldschmidt;Su Yin Bianca Maria Soen;L. Franzen;J. Rochaix
通讯作者:
J. Rochaix
影响因子:
--
作者:
A. Barkan
通讯作者:
A. Barkan
DOI:
10.1071/pp9950285
发表时间:
1995
期刊:
Australian Journal of Plant Physiology
影响因子:
--
作者:
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通讯作者:
Badger
影响因子:
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作者:
Moreira, D;Philippe, H
通讯作者:
Philippe, H
影响因子:
5.1
作者:
D. Stahl;S. Rodermel;L. Bogorad;A. Subramanian
通讯作者:
A. Subramanian