An experiment assessing effects of personalized feedback about genetic susceptibility to obesity on attitudes towards diet and exercise.

An experiment assessing effects of personalized feedback about genetic susceptibility to obesity on attitudes towards diet and exercise.
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DOI:
10.1016/j.appet.2017.08.021
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发表时间:
2018-01-01
期刊:
影响因子:
5.4
通讯作者:
Lebowitz MS
Lebowitz MS
中科院分区:
医学2区
文献类型:
--
作者:
Ahn WK;Lebowitz MS

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随着人们越来越关注遗传因素对肥胖易感性的影响,最近的研究已经探讨了遗传因素如何影响外行人与体重有关的态度和饮食行为。然而,很少有人考虑到学习没有肥胖遗传倾向的潜在影响。目前的研究调查了这种反馈可能会带来负面影响的可能性,使人们觉得自己不会受到体重增加的伤害,这被称为遗传无敌效应。在进行了一项伪装成基因筛查的唾液测试后,参与者被随机分配,告知他们携带已知会增加肥胖风险的基因的可能性非常高或非常低。那些被告知自己没有遗传上的肥胖倾向的参与者对健康饮食和运动习惯的疗效的判断,明显低于那些被告知自己有遗传上的肥胖倾向和没有得到任何遗传反馈的参与者。当被提示从菜单中选择一餐时,那些被告知自己在基因上没有肥胖倾向的参与者也比其他人更有可能选择不健康的食物。这些研究结果证明了遗传无敌效应的存在,表明表明没有遗传缺陷的个性化反馈可能会产生负面的心理后果,并对健康产生重大影响。
As increasing attention is paid to possible genetic influences on susceptibility to obesity, recent studies have examined how genetic attributions can impact laypeople’s weight-related attitudes and eating behavior. Little consideration, however, has been devoted to understanding the potential effects of learning that one does not have a genetic predisposition to obesity. The present study investigated the possibility that such feedback might bring about negative consequences by making people feel invulnerable to weight gain, which is termed a genetic invincibility effect. After conducting a saliva test disguised as genetic screening, participants were randomly assigned to be told that there was either a very high or very low chance that they carried genes known to increase one’s risk of developing obesity. Participants who were told that they were not genetically predisposed to obesity judged the efficacy of healthy diet and exercise habits to be significantly lower than did those who were told that they were genetically predisposed and those who did not receive any genetic feedback. When prompted to select a meal from a menu of options, participants who were told that they were not genetically predisposed to obesity were also more likely than others to select unhealthy foods. These findings demonstrate the existence of a genetic invincibility effect, suggesting that personalized feedback indicating the absence of a genetic liability could have negative psychological consequences with substantial health-related implications.
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DOI: 10.1038/oby.2011.324
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期刊: OBESITY
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