Polyethylene Glycol Electrolyte Lavage Solution versus Colonic Hydrotherapy for Bowel Preparation before Colonoscopy: A Single Center, Randomized, and Controlled Study.

Polyethylene Glycol Electrolyte Lavage Solution versus Colonic Hydrotherapy for Bowel Preparation before Colonoscopy: A Single Center, Randomized, and Controlled Study.
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聚乙二醇电解质灌洗液与结肠水疗在结肠镜检查前肠道准备的比较:单中心、随机、对照研究

DOI:
10.1155/2014/541586
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发表时间:
2014
影响因子:
2
通讯作者:
Lan CH
Lan CH
中科院分区:
医学4区
文献类型:
--
作者:
Cao Y;Zhang KY;Li J;Lu H;Xie WL;Liao ST;Chen DF;Zeng DF;Lan CH

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这项单中心、随机、对照研究旨在比较聚乙二醇电解质灌洗(PEG-EL)溶液和结肠水疗法(CHT)用于结肠镜检查前肠道准备的有效性和安全性。共有196名符合条件的门诊患者被随机分配到PEG-EL(n = 102)或CHT(n = 94)组。主要结果指标包括结肠清洁度和不良反应。次要结局指标为患者满意度和偏好、结肠镜检查结果、回盲部到达率、检查者满意度和盲肠插管时间。结果显示,PEG-EL组的结肠清洁度明显优于CHT组,不良反应较少,检查者满意度增加。然而,CHT组有更高的患者满意度和更高的憩室病检出率。两组回盲部到达率及患者偏好均无显著差异(P > 0.05)。这些结果表明,PEG-EL是完全遵循准备说明的患者的首选。
This single center, randomized, and controlled study aimed to compare the effectiveness and safety of polyethylene glycol electrolyte lavage (PEG-EL) solution and colonic hydrotherapy (CHT) for bowel preparation before colonoscopy. A total of 196 eligible outpatients scheduled for diagnostic colonoscopy were randomly assigned to the PEG-EL (n = 102) or CHT (n = 94) groups. Primary outcome measures included colonic cleanliness and adverse effects. Secondary outcome measures were patient satisfaction and preference, colonoscopic findings, ileocecal arrival rate, examiner satisfaction, and cecal intubation time. The results show that PEG-EL group was associated with significantly better colonic cleanliness than CHT group, fewer adverse effects, and increased examiner satisfaction. However, the CHT group had higher patient satisfaction and higher diverticulosis detection rates. Moreover, the results showed the same ileocecal arrival rate and patient preference between the two groups (P > 0.05). These findings indicate that PEG-EL is the preferred option in patients who followed the preparation instructions completely.
胃肠道癌症患者中检测到的 MLH1 和 MSH2 基因错义突变与外显子剪接增强子和沉默子相关
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