Molecules to modeling: Toxoplasma gondii oocysts at the human-animal-environment interface.

Molecules to modeling: Toxoplasma gondii oocysts at the human-animal-environment interface.
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DOI:
10.1016/j.cimid.2012.10.006
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发表时间:
2013-05
期刊:
Comparative immunology, microbiology and infectious diseases
影响因子:
--
通讯作者:
Conrad PA
Conrad PA
中科院分区:
其他
文献类型:
--
作者:
VanWormer E;Fritz H;Shapiro K;Mazet JA;Conrad PA

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Environmental transmission of extremely resistant Toxoplasma gondii oocysts has resulted in infection of diverse species around the world, leading to severe disease and deaths in human and animal populations. This review explores T. gondii oocyst shedding, survival, and transmission, emphasizing the importance of linking laboratory and landscape from molecular characterization of oocysts to watershed-level models of oocyst loading and transport in terrestrial and aquatic systems. Building on discipline-specific studies, a One Health approach incorporating tools and perspectives from diverse fields and stakeholders has contributed to an advanced understanding of T. gondii and is addressing transmission at the rapidly changing human–animal–environment interface.
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