Associations between symptoms of posttraumatic stress disorder, pain, and alcohol use disorder among OEF/OIF/OND veterans.

Associations between symptoms of posttraumatic stress disorder, pain, and alcohol use disorder among OEF/OIF/OND veterans.
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DOI:
10.1016/j.addbeh.2021.107031
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发表时间:
2021-11
影响因子:
4.4
通讯作者:
Pedersen ER
Pedersen ER
中科院分区:
医学2区
文献类型:
--
作者:
Saba SK;Davis JP;Prindle JJ;Castro CA;Pedersen ER

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酒精使用障碍(AUD)在持久自由行动、伊拉克自由行动和新黎明行动(OEF/OIF/OND)退伍军人中很普遍。疼痛和创伤后应激障碍(PTSD)高度并存,增加了患AUD的风险。以前将疼痛或创伤后应激障碍与AUD联系起来的研究还没有探索疼痛和创伤后应激障碍症状之间的相互作用。OEF/OIF/OND退伍军人(N=1230)是从社交媒体网站招募的,作为退伍军人健康行为横断面研究的一部分。使用疼痛结果问卷对疼痛进行评估。创伤后应激障碍症状和创伤后应激障碍症状群使用DSM-5创伤后应激障碍检查表进行评估。用AUD辨别测验评定AUD症状。使用线性回归模型检验主效应和交互效应在全样本中和按性别分开。疼痛和PTSD症状都与AUD症状增加有关,尽管疼痛和AUD之间的关系在PTSD症状相对较低时更高。在创伤后应激障碍症状群方面,重新体验和消极的认知和情绪与AUD症状的增加有关。揭示了疼痛与再体验以及疼痛与回避之间的相互作用。男性的结果反映了整个样本,而女性的疼痛与负面认知和情绪之间的相互作用与AUD有关。结果强调了退伍军人中AUD、创伤后应激障碍症状和疼痛之间的联系。虽然在创伤后应激障碍症状较低的情况下,疼痛和AUD之间的关系似乎更强,但这两种情况都与AUD增加相关。治疗退伍军人AUD的临床医生应该考虑到潜在的并存范围。
Alcohol use disorder (AUD) is prevalent among Operation Enduring Freedom, Operation Iraqi Freedom, and Operation New Dawn (OEF/OIF/OND) veterans. Pain and posttraumatic stress disorder (PTSD) are highly comorbid and increase risk of AUD. Prior studies linking pain or PTSD to AUD have not explored interactions between pain and PTSD symptoms. OEF/OIF/OND veterans (N=1,230) were recruited from social media websites as part of a cross-sectional study of veteran health behavior. Pain was assessed using the Pain Outcomes Questionnaire. PTSD symptoms and PTSD symptom clusters were assessed using the Posttraumatic Stress Disorder Checklist for DSM-5. AUD symptoms were assessed with the AUD Identification Test. Linear regression models were used to test for main and interaction effects in the full sample and separately by sex. Both pain and PTSD symptoms were associated with increased AUD symptomology, though the relationship between pain and AUD was heighted at relatively low PTSD symptoms. With respect to PTSD symptom clusters, re-experiencing and negative cognitions and mood were associated with increased AUD symptomology. Interactions between pain and re-experiencing as well as pain and avoidance were revealed. Results for men mirrored the full sample, while an interaction between pain and negative cognitions and mood was associated with AUD in women. Results highlight associations between AUD, PTSD symptoms, and pain among veterans. While the relationship between pain and AUD appeared stronger in the context of low PTSD symptoms, both conditions were associated with increased AUD. Clinicians treating veterans with AUD should address the range of potential comorbidities.
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