A Novel Audiovisual Brain-Computer Interface and Its Application in Awareness Detection.
A Novel Audiovisual Brain-Computer Interface and Its Application in Awareness Detection.
复制标题
一种新型视听脑机接口及其在意识检测中的应用
DOI：
10.1038/srep09962
复制
发表时间：
2015-06-30
影响因子：
4.6
通讯作者：
Li Y
中科院分区：
文献类型：
--
作者：
Wang F;He Y;Pan J;Xie Q;Yu R;Zhang R;Li Y
目前，检测意识障碍（DOC）患者的意识是一项具有挑战性的任务，通常通过行为观察量表（如JFK昏迷恢复量表-修订版）来解决。脑机接口（bci）提供了一种检测DOC患者意识的替代方法。然而，与健康个体相比，这些患者使用脑机接口的能力要低得多。本研究提出了一种新的脑机接口，使用时间、空间和语义上一致的涉及数字（即视觉和口头数字）的视听刺激。受试者被指示选择性地注意由指示提示的目标刺激。10名健康受试者首先参与实验，对该系统进行评估。结果表明，视听BCI系统优于单纯听觉和单纯视觉BCI系统。通过事件相关电位分析，我们观察到目标刺激的视听整合效应，增强了大脑对目标刺激和非目标刺激反应的区分能力，从而提高了视听脑机接口的性能。然后应用该系统检测了7名DOC患者的意识，其中5名患者表现出命令遵循和数字识别。因此，这种视听脑机接口系统可以作为一种支持性床边工具，用于DOC患者的意识检测。
Currently, detecting awareness in patients with disorders of consciousness (DOC) is a challenging task, which is commonly addressed through behavioral observation scales such as the JFK Coma Recovery Scale-Revised. Brain-computer interfaces (BCIs) provide an alternative approach to detect awareness in patients with DOC. However, these patients have a much lower capability of using BCIs compared to healthy individuals. This study proposed a novel BCI using temporally, spatially and semantically congruent audiovisual stimuli involving numbers (i.e., visual and spoken numbers). Subjects were instructed to selectively attend to the target stimuli cued by instruction. Ten healthy subjects first participated in the experiment to evaluate the system. The results indicated that the audiovisual BCI system outperformed auditory-only and visual-only systems. Through event-related potential analysis, we observed audiovisual integration effects for target stimuli, which enhanced the discriminability between brain responses for target and nontarget stimuli and thus improved the performance of the audiovisual BCI. This system was then applied to detect the awareness of seven DOC patients, five of whom exhibited command following as well as number recognition. Thus, this audiovisual BCI system may be used as a supportive bedside tool for awareness detection in patients with DOC.
登录
查看更多内容
DOI：
10.1111/j.1749-6632.2008.04122.x
发表时间：
2009-01-01
期刊：
DISORDERS OF CONSCIOUSNESS
影响因子：
--
作者：
Kuebler, Andrea;Furdea, Adrian;Kotchoubey, Boris
通讯作者：
Kotchoubey, Boris
DOI：
10.1109/86.847808
发表时间：
2000-06-01
期刊：
IEEE TRANSACTIONS ON REHABILITATION ENGINEERING
影响因子：
--
作者：
Donchin, E;Spencer, KM;Wijesinghe, R
通讯作者：
Wijesinghe, R
影响因子：
3.7
作者：
Calvert, GA
通讯作者：
Calvert, GA
影响因子：
16.2
作者：
Amedi, A;Malach, R;Pascual-Leone, A
通讯作者：
Pascual-Leone, A
影响因子：
3.7
作者：
Furdea, A.;Halder, S.;Kuebler, A.
通讯作者：
Kuebler, A.