Day-to-day Relationships between Physical Activity and Sleep Characteristics among People with Heart Failure and Insomnia.

Day-to-day Relationships between Physical Activity and Sleep Characteristics among People with Heart Failure and Insomnia.
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DOI:
10.1080/15402002.2020.1824918
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发表时间:
2021-09
影响因子:
3.1
通讯作者:
Redeker NS
Redeker NS
中科院分区:
医学3区
文献类型:
--
作者:
Ash G;Jeon S;Conley S;Knies AK;Yaggi HK;Jacoby D;Hollenbeak CS;Linsky S;O'Connell M;Redeker NS

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研究心力衰竭(HF)和失眠患者的身体活动(PA)和睡眠特征之间的双向关系。97名社区居民成年人[中位年龄61.9(四分位距55.3,70.9)岁,女性41%]患有稳定的HF和失眠(失眠严重程度指数>7)。这项子研究纵向分析了连续15天和15夜的腕动记录,这些记录是在参与失眠症认知行为治疗的随机对照试验之前收集的基线数据。我们使用两个级别的混合模型内(每日)和参与者之间的变化来预测白天PA计数/分钟从睡眠变量(总睡眠时间,睡眠效率)和预测睡眠变量从PA。PA计数/min低于既往无HF的队列(209(166,259)),与NYHA分级(标准化系数βs=−0.14,p<0.01)、年龄(βs=−0.13,p=0.01)、合并症(βs=−0.19,p<0.01)和体重指数(βs=−0.12,p=0.04)呈负相关。校正所有显著协变量后,NYHA 2-4级HF受试者中总睡眠时间与次日PA的受试者内相关性估计为正(βs=0.09,p=0.01),而年龄≥60岁的受试者中PA与同夜总睡眠时间的受试者内相关性估计为正(βs=0.10,p=0.03)。根据年龄和HF级别,白天PA与同夜睡眠时间更长相关和/或睡眠时间更长与第二天PA更大相关。在那些更严重的HF患者中,现实的睡眠改善与第二天有临床意义的PA增加相关。
Examine the bidirectional relationships between within-person day-to-day fluctuations in physical activity (PA) and sleep characteristics among people with heart failure (HF) and insomnia. Ninety-seven community-dwelling adults [median age 61.9 (interquartile range 55.3,70.9) years, female 41%] with stable HF and insomnia (insomnia severity index >7). This sub-study longitudinally analyzed 15 consecutive days and nights of wrist actigraphy recordings, that were collected for baseline data prior to participation in a randomized controlled trial of cognitive behavioral therapy for insomnia. We used two-level mixed models of within- (daily) and between-participants variation to predict daytime PA counts/min from sleep variables (total sleep time, sleep efficiency) and predict sleep variables from PA. PA counts/min were low compared to prior cohorts that did not have HF (209 (166,259)) and negatively associated with NYHA class (standardized coefficient βs=−0.14, p<0.01), age (βs=−0.13, p=0.01), comorbidities (βs=−0.19, p<0.01), and body mass index (βs=−0.12, p=0.04). After adjustment for all significant covariates, the within-participant association of total sleep time with next-day PA was estimated to be positive among participants with NYHA class 2-4 HF (βs=0.09, p=0.01), while the within-participant association of PA with same-night total sleep time was estimated to be positive among participants aged ≥60 years (βs=0.10, p=0.03). Depending upon age and HF class, daytime PA was associated with longer same-night sleep and/or longer sleep was associated with greater next-day PA. Among those with more advanced HF, realistic sleep improvements were associated with clinically meaningful PA gains the next day.
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