Physical activity and self-reported symptoms of insomnia, restless legs syndrome, and depression: the comprehensive dialysis study.

Physical activity and self-reported symptoms of insomnia, restless legs syndrome, and depression: the comprehensive dialysis study.
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DOI:
10.1111/j.1542-4758.2012.00726.x
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发表时间:
2013-01
期刊:
Hemodialysis international. International Symposium on Home Hemodialysis
影响因子:
--
通讯作者:
Chertow GM
Chertow GM
中科院分区:
其他
文献类型:
--
作者:
Anand S;Johansen KL;Grimes B;Kaysen GA;Dalrymple LS;Kutner NG;Chertow GM

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睡眠和情绪障碍的症状在接受透析的患者中很常见,并与存活率和与健康相关的生活质量显著下降有关。我们使用综合透析研究(CDS)的数据来检验在新接受透析的患者中,自我报告的体力活动与自我报告的失眠、不宁腿综合征(RLS)和抑郁症状的相关性。CDS收集了1678名腹膜(n=169)或血液透析(n=1509)患者的体力活动、功能状态和与健康相关的生活质量的数据。人类活动概况被用来衡量自我报告的体力活动。症状的引出方式如下:失眠使用三个问题来捕捉启动或维持睡眠的困难,RLS使用基于美国国立卫生研究院研讨会的三个问题,以及抑郁症使用两个项目的患者健康问卷。我们获得了1636名失眠和抑郁症状的数据,以及1622名(98%)RLS患者的症状数据。其中,863人(53%)报告三种失眠症状中的一种持续发生。477例(29%)患者出现RLS症状,451例(28%)患者出现抑郁症状。在对人口统计学、共病情况和实验室变量进行调整的模型中,人类活动概况的调整后的活动分数与所有三种情况呈负相关。睡眠和情绪障碍在我们大量不同的新接受透析的患者中被普遍报道。报告体力活动水平较低的患者更有可能报告失眠、RLS和抑郁症状。
Symptoms of sleep and mood disturbances are common among patients on dialysis and are associated with significant decrements in survival and health-related quality of life. We used data from the Comprehensive Dialysis Study (CDS) to examine the association of self-reported physical activity with self-reported symptoms of insomnia, restless legs syndrome (RLS) and depression in patients new to dialysis. The CDS collected data on physical activity, functional status, and health-related quality of life from 1678 patients on either peritoneal (n=169) or hemodialysis (n=1509). The Human Activity Profile was used to measure self-reported physical activity. Symptoms were elicited in the following manner: insomnia using three questions designed to capture difficulty in initiating or maintaining sleep, RLS using three questions based on the National Institutes of Health workshop, and depression using the 2-item Patient Health Questionnaire. We obtained data on symptoms of insomnia and depression for 1636, and on symptoms of RLS for 1622 (>98%) patients. Of these, 863 (53%) reported one of three insomnia symptoms as occurring at a persistent frequency. Symptoms of RLS and depression occurred in 477 (29%) and 451 (28%) of patients, respectively. The Adjusted Activity Score of the Human Activity Profile was inversely correlated with all three conditions in models adjusting for demographics, comorbid conditions, and laboratory variables. Sleep and mood disturbances were commonly reported in our large, diverse cohort of patients new to dialysis. Patients who reported lower levels of physical activity were more likely to report symptoms of insomnia, RLS and depression.
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