Reduced Synchronization in the Visual Cortex of Cats with Strabismic Amblyopia
Reduced Synchronization in the Visual Cortex of Cats with Strabismic Amblyopia
复制标题
患有斜视弱视的猫视觉皮层的同步性降低
DOI：
10.1111/j.1460-9568.1994.tb00556.x
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发表时间：
1994
影响因子：
3.4
通讯作者：
W. Singer
中科院分区：
文献类型：
--
作者：
P. Roelfsema;P. König;A. Engel;R. Sireteanu;W. Singer
在斜视猫的视觉皮层17区，使用多电极记录研究了空间分离神经元的同步放电，斜视猫已发展为行为验证的斜视眼弱视。用不同空间频率的移动光条或光栅诱发神经元的反应。正常眼驱动的神经元比弱视眼主导的神经元显示出更强的反应同步性。这些眼间差异是非常显着的，特别是明显的高空间频率的光栅刺激。没有注意到两眼间的差异，相对于光条和光栅的反应幅度。这些结果表明，减少作为斜视性弱视的神经生理学相关的人口反应的同步性，并强调相关的空间分离的皮层神经元的视觉信息的正常处理的重要性。
Synchronous firing of spatially separate neurons was studied with multi‐electrode recordings in area 17 of the visual cortex of strabismic cats which had developed behaviourally verified amblyopia of the deviated eye. Responses of neurons were evoked with moving light bars or gratings of different spatial frequency. Neurons driven by the normal eye displayed stronger synchronization of their responses than neurons dominated by the amblyopic eye. These interocular differences were highly significant and particularly pronounced for grating stimuli of high spatial frequency. No interocular differences were noted with respect to the amplitudes of responses to the light bars and gratings. These results suggest reduced synchronization of population responses as a neurophysiological correlate of strabismic amblyopia and underline the importance of correlated firing of spatially separate cortical neurons for normal processing of visual information.
哺乳动物视觉皮层局部回路的发育。
影响因子：
13.9
作者：
Katz,LC;Callaway,EM
通讯作者：
Callaway,EM
影响因子：
2.5
作者：
CHINO, YM;SHANSKY, MS;BANSER, FA
通讯作者：
BANSER, FA
斜视猫的空间视觉。
影响因子：
2.5
作者：
Holopigian,K;Blake,R
通讯作者：
Blake,R