Reducing the risk of HIV infection during pregnancy among South African women: a randomized controlled trial.
Reducing the risk of HIV infection during pregnancy among South African women: a randomized controlled trial.
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DOI：
10.1080/09540121.2013.772280
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发表时间：
2013
期刊：
影响因子：
1.7
通讯作者：
Weiss SM
中科院分区：
文献类型：
--
作者：
Jones DL;Peltzer K;Villar-Loubet O;Shikwane E;Cook R;Vamos S;Weiss SM
南非姆普马兰加省是孕妇艾滋病毒/艾滋病诊断率最高的省份之一（约29.4%）。本研究旨在提高男性参与怀孕，以增加艾滋病毒的披露，性交流，艾滋病毒的知识和减少无保护的性行为。参加产前诊所（ANC）的参与者完成了艾滋病毒咨询和检测，并与男性伴侣（n = 239对夫妇，478人）登记。12名ANC被随机分配提供预防母婴传播（PMTCT）干预或标准护理，健康教育课程加PMTCT。在基线和干预后（基线后约6-8周）对参与者进行了人口统计学、性行为、艾滋病毒相关知识和冲突解决策略的评估。实验参与者增加了艾滋病毒知识，使用谈判，减少亲密伴侣暴力。此外，从基线到干预后，他们更有可能增加避孕套的使用（OR = 5.1，95% CI =（2.0，13.3））。对照条件下的血清转化率超过实验值（6 vs. 0）。在实验或对照条件下，向伴侣披露艾滋病毒血清状态的男性或女性并没有随着时间的推移而增加。男性参与怀孕可能是减少性风险行为和艾滋病毒传播的重要策略。结果支持实用的团体干预措施，以加强怀孕夫妇之间的沟通和艾滋病毒知识。
Mpumalanga Province, South Africa has one of the highest HIV/AIDS diagnosis rates among pregnant women (~29.4%). This study sought to enhance male involvement in pregnancy to increase HIV disclosure, sexual communication, HIV knowledge and reduce unprotected sex. Participants attending Antenatal Clinics (ANC) completed HIV counselling and testing and were enrolled with male partners (n = 239 couples, 478 individuals). Twelve ANCs were randomly assigned to provide a prevention of mother-to-child transmission (PMTCT) intervention or the standard of care, health education sessions plus PMTCT. Participants were assessed at baseline and post-intervention (approximately 6–8 weeks post-baseline) on demographics, sexual behaviour, HIV-related knowledge, and conflict resolution strategies. Experimental participants increased HIV knowledge, use of negotiation, and decreased intimate partner violence. Additionally, they were more likely to have increased condom use from baseline to post-intervention (OR = 5.1, 95% CI = (2.0, 13.3)). Seroconversions in the control condition exceeded experimental (6 vs. 0). HIV serostatus disclosure to partner did not increase over time for men or women within the experimental or control condition. Male involvement in pregnancy may be an important strategy to reduce sexual risk behavior and HIV transmission. Results support the utility of group interventions to enhance communication and HIV knowledge among pregnant couples.
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DOI：
10.1097/qad.0b013e32834a9338
发表时间：
2011-09-24
期刊：
AIDS (London, England)
影响因子：
--
作者：
Mugo NR;Heffron R;Donnell D;Wald A;Were EO;Rees H;Celum C;Kiarie JN;Cohen CR;Kayintekore K;Baeten JM;Partners in Prevention HSV/HIV Transmission Study Team
通讯作者：
Partners in Prevention HSV/HIV Transmission Study Team
影响因子：
3.8
作者：
Peltzer, K.;Mlambo, G.
通讯作者：
Mlambo, G.
影响因子：
2.7
作者：
Maman, Suzanne;Moodley, Dhayendre;Groves, Allison K.
通讯作者：
Groves, Allison K.
影响因子：
3.8
作者：
Moodley, Dhayendre;Esterhuizen, Tonya M.;Ngaleka, Linda
通讯作者：
Ngaleka, Linda
DOI：
10.1097/qai.0b013e3181d61c2e
发表时间：
2010-07
期刊：
Journal of acquired immune deficiency syndromes (1999)
影响因子：
--
作者：
Chen YQ;Young A;Brown ER;Chasela CS;Fiscus SA;Hoffman IF;Valentine M;Emel L;Taha TE;Goldenberg RL;Read JS
通讯作者：
Read JS