Prevalence of prehypertension and associated cardiovascular risk profiles among prediabetic Omani adults.
Prevalence of prehypertension and associated cardiovascular risk profiles among prediabetic Omani adults.
复制标题
糖尿病前期成年人的高素质前和相关心血管风险特征的患病率。
DOI：
10.1186/1471-2458-8-108
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发表时间：
2008-04-07
影响因子：
4.5
通讯作者：
Duttagupta, Kalyan Kanti
中科院分区：
文献类型：
--
作者：
Ganguly, Shyam Sundar;Al-Shafaee, Mohammed Ali;Bhargava, Kamlesh;Duttagupta, Kalyan Kanti
糖尿病前期和高血压前期的重要性已在几项研究中得到证实，特别是对于CVD的一级预防。最近一项基于社区的横断面研究显示，40.9%的阿曼成年人是糖尿病前期患者。本研究旨在评估糖尿病前期患者高血压前期的患病率和相关的心血管危险因素。据我们所知，这是关于这一问题的第一份报告。该研究包括327名确诊的糖尿病前期阿曼成年人，分析了他们的人口统计学，代谢和行为特征。比较三个不同血压组之间的这些特征，以确定CVD的危险因素。采用单因素和逐步多元Logistic回归方法对数据进行分析。在这项研究中，高血压前期的患病率为54.1%。男性发生高血压前期的危险性高于女性（OR = 2.30，95% CI：1.21，4.38; P < 0.01）。BMI越高，发生高血压前期的危险性越高（OR = 2.25，95% CI：1.26，4.02; P < 0.01）。OGT水平升高可增加高血压前期发生的危险性（OR = 1.26，95% CI：1.06，1.50; P < 0.01）。高血压前期的患病率很高（54.1%）。在这些糖尿病前期受试者中，高血压前期的主要决定因素是男性，增加的精神障碍和BMI。提出了相应的干预策略。
The importance of prediabetes and prehypertension has been demonstrated in several studies especially for primary prevention of CVD. A recent community based cross-sectional study revealed that 40.9 percent Omani adults are prediabetics. This study was undertaken to estimate the prevalence of prehypertension and associated cardiovascular risk profiles in prediabetics. To best of our knowledge, this is the first report on this subject. The study included 327 confirmed pre-diabetic Omani adults, who were analysed for their demographic, metabolic and behavioral characteristics. These characteristics were compared between the three different blood pressure groups to determine the CVD risk factors. Univariate and step-wise multiple logistic regression methods were used to carry out the analysis of the data. In this study, the prevalence of prehypertension was 54.1 percent. Males were at higher risk of developing prehypertension as compared to females (OR = 2.30, 95% CI: 1.21, 4.38; P < 0.01). The individuals with higher BMI have two fold more risk of developing prehypertension (OR = 2.25, 95% CI: 1.26, 4.02; P < 0.01). The increased level of OGT enhanced the risk of developing prehypertension (OR = 1.26, 95% CI: 1.06, 1.50; P < 0.01). A high prevalence of prehypertension (54.1%) exists in this study population. The major determinants of prehypertension in these prediabetic subjects were male gender, increasing dysglycemia and BMI. Appropriate intervention strategies have been suggested.
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影响因子：
2.7
作者：
Hassan, MO;Al Kharusi, W;Ziada, A
通讯作者：
Ziada, A
影响因子：
5.6
作者：
Winegarden, CR
通讯作者：
Winegarden, CR
影响因子：
8.3
作者：
Zhang, Y;Lee, ET;Howard, BV
通讯作者：
Howard, BV
影响因子：
4.7
作者：
Washio M;Tokunaga S;Yoshimasu K;Kodama H;Liu Y;Sasazuki S;Tanaka K;Kono S;Mohri M;Takeshita A;Arakawa K;Ideishi M;Nii T;Shirai K;Arai H;Doi Y;Kawano T;Nakagaki O;Takada K;Hiyamuta K;Koyanagi S
通讯作者：
Koyanagi S
影响因子：
16.2
作者：
Buse, John B.;Ginsberg, Henry N.;Stone, Neil J.
通讯作者：
Stone, Neil J.