Urinary symptoms in breast cancer: a systematic review.
Urinary symptoms in breast cancer: a systematic review.
复制标题
DOI：
10.1002/cncr.26324
复制
发表时间：
2012-02-01
期刊：
影响因子：
6.2
通讯作者：
Wyman JF
中科院分区：
文献类型：
--
作者：
Donovan KA;Boyington AR;Ismail-Khan R;Wyman JF
大量的研究已经记录了乳腺癌幸存者中绝经期症状，特别是血管炎症状的患病率和严重程度及其对生活质量的影响。然而，作为更年期症状的一部分，泌尿系统症状受到的关注相对较少。因此，对乳腺癌幸存者泌尿系统症状的患病率和严重程度知之甚少。我们对1990年至2010年间发表的研究进行了系统回顾，以描述乳腺癌幸存者泌尿系统症状的患病率和严重程度。我们确定了16项合格的研究，涉及2,500多名妇女。研究的目的、设计和样本性质各不相同;大多数研究使用相同的泌尿系统症状定义和评估方法。症状的患病率范围从12%的女性报告排尿时有烧灼感或疼痛到58%的女性报告膀胱控制困难。虽然在许多研究中，最大比例的女性将症状评为轻度，但多达23%的女性报告了严重的症状。轻度至中度的泌尿系统症状在乳腺癌幸存者中很常见，一些妇女报告有严重的症状。这些症状似乎对妇女的生活质量产生不利影响。有必要进行更多的研究，评估泌尿系统症状的自然史，使用共识的定义和验证措施，在不同的人群。尽管如此，本综述建议临床医生应筛查乳腺癌幸存者的泌尿系统症状，并提供治疗建议或酌情转诊。
A large body of research has documented the prevalence and severity of menopausal symptoms, especially vasomotor symptoms, in breast cancer survivors and their impact on quality of life. Urinary symptoms as part of the constellation of menopausal symptoms, however, have received relatively little attention. Thus, less is known about the prevalence and severity of urinary symptoms in breast cancer survivors. We conducted a systematic review of studies published between 1990 and 2010 to describe the prevalence and severity of urinary symptoms in breast cancer survivors. We identified 16 eligible studies involving more than 2,500 women. Studies varied with respect to purpose, design, and nature of samples included; the majority used the same definition and assessment approach for urinary symptoms. Prevalence rates for symptoms ranged from 12% of women reporting burning or pain on micturition to 58% reporting difficulty with bladder control. Although in many studies the largest percentage of women rated symptoms as mild, as many as 23% reported severe symptoms. Mild to moderate urinary symptoms are common in breast cancer survivors and some women report severe symptoms. Symptoms appear to adversely affect women’s quality of life. There is a need for additional research assessing the natural history of urinary symptoms using consensus definitions and validated measures in diverse populations. Nevertheless, this review suggests that clinicians should screen for urinary symptoms in breast cancer survivors and offer treatment recommendations or make referrals as appropriate.
登录
查看更多内容
影响因子：
120.7
作者：
Holroyd-Leduc, Jayna M.;Tannenbaum, Cara;Straus, Sharon E.
通讯作者：
Straus, Sharon E.
DOI：
10.1046/j.1532-5415.2001.49094.x
发表时间：
2001-04-01
影响因子：
6.3
作者：
Dugan, E;Roberts, CP;Albertson, E
通讯作者：
Albertson, E
DOI：
10.1034/j.1600-0412.2001.801117.x
发表时间：
2001-11-01
影响因子：
4.3
作者：
Hägglund, D;Walker-Engström, ML;Leppert, J
通讯作者：
Leppert, J
DOI：
10.1097/00042192-200103000-00006
发表时间：
2001-03-01
影响因子：
2.7
作者：
Greendale, GA;Petersen, L;Ganz, PA
通讯作者：
Ganz, PA
影响因子：
45.3
作者：
Avis, NE;Crawford, S;Manuel, J
通讯作者：
Manuel, J