Facile synthesis of N-doped carbon dots for direct/indirect detection of heavy metal ions and cell imaging
Facile synthesis of N-doped carbon dots for direct/indirect detection of heavy metal ions and cell imaging
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轻松合成氮掺杂碳点，用于直接/间接检测重金属离子和细胞成像
DOI：
10.1007/s11356-020-11880-z
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发表时间：
2021-01
影响因子：
5.8
通讯作者：
Zideng Gao
中科院分区：
文献类型：
--
作者：
Zijun Xu;Jin Liu;Kejia Wang;Binwei Yan;Shuwen Hu;Xueqin Ren;Zideng Gao
本研究建立了一种简便、快速、节能、灵敏的测定Fe3+和Cr（VI）的方法。以l -精氨酸和d -葡萄糖为原料，通过水热法合成了光致发光量子产率为21%的l -精氨酸/ d -葡萄糖碳量子点（Arg/Glu-CQDs）。在365 nm激发波长下，Arg/Glu-CQDs的最大发射波长为450 nm。此外，与Fe2+和其他金属离子相比，Arg/Glu-CQDs对Fe3+表现出敏感和选择性的响应。当Arg/Glu-CQDs与Fe3+混合时，其荧光明显被内滤效应（IFE）猝灭。因此，Arg/Glu-CQDs/Fe2+体系可以选择性地检测Cr(VI)；Cr（VI）能将Fe2+氧化为Fe3+，使荧光猝灭。该荧光传感器系统（Arg/Glu-CQDs/Fe2+系统）对河流水样中Fe3+和Cr（VI）的检测具有较高的灵敏度和良好的选择性。检测效率为97.07 ~ 103.46%。以A549细胞为靶点，采用MTT法评价Arg/Glu-CQDs的细胞毒性，拓展Arg/Glu-CQDs在生物系统中的应用；MTT试验表明Arg/Glu-CQDs无细胞毒性。Arg/Glu-CQDs也在A549细胞中成功成像，这表明了在生物成像方面的进一步应用可能性。图形抽象
In this study, an approach for the facile, rapid, energy-saving, and sensitive determination of Fe3+and Cr(VI) was developed. L-arginine/D-glucose carbon quantum dots (Arg/Glu-CQDs), with a photoluminescence quantum yield of 21%, were synthesized from L-arginine and D-glucose through a facile, hydrothermal process. The maximum emission wavelength of Arg/Glu-CQDs was observed at 450 nm, under an excitation wavelength of 365 nm. In addition, Arg/Glu-CQDs exhibited a sensitive and selective response to Fe3+compared to Fe2+and other metal ions. The Arg/Glu-CQDs’ fluorescence was noticeably quenched through the inner filter effect (IFE) when Arg/Glu-CQDs were mixed with Fe3+. Accordingly, the Arg/Glu-CQDs/Fe2+system could selectively detect Cr(VI); Cr(VI) could oxidize Fe2+to Fe3+and quench the fluorescence. The fluorescence sensor system (i.e., the Arg/Glu-CQDs/Fe2+system) showed high sensitivity and excellent selectivity for the detection of Fe3+and Cr(VI) in river water samples. Satisfactory detection efficiencies ranging from 97.07 to 103.46% were obtained. The cytotoxicity of Arg/Glu-CQDs was evaluated through an MTT assay using A549 cells as the target, to extend the application of Arg/Glu-CQDs to biological systems; the MTT assay indicated that the Arg/Glu-CQDs is non-cytotoxicity. Arg/Glu-CQDs were also successfully imaged in A549 cells indicating further application possibilities in bioimaging.Graphical abstract
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DOI：
10.1016/j.jphotochem.2018.12.028
发表时间：
2019-03
期刊：
Journal of Photochemistry and Photobiology A: Chemistry
影响因子：
--
作者：
R. V;S. Misra;M. Santra;Divya P Ottoor
通讯作者：
R. V;S. Misra;M. Santra;Divya P Ottoor
影响因子：
3.3
作者：
Neetu Chauhan;Satyesh Raj Anand;R. Aggarwal;J. Kaushik;Sandeep Singh Shekhawat;A. Sonker;S. Sonkar-S.-Sonka
通讯作者：
Neetu Chauhan;Satyesh Raj Anand;R. Aggarwal;J. Kaushik;Sandeep Singh Shekhawat;A. Sonker;S. Sonkar-S.-Sonka
影响因子：
2.9
作者：
Ju-woon Lee;Sang-Hee Oh;Jae‐Hun Kim;Eui-Hong Byun;M. Kim;Min Baek;M. Byun
通讯作者：
Ju-woon Lee;Sang-Hee Oh;Jae‐Hun Kim;Eui-Hong Byun;M. Kim;Min Baek;M. Byun
影响因子：
1.7
作者：
Mark T. Stauffer;Leland J. Hunter;Steven K. Troncone
通讯作者：
Mark T. Stauffer;Leland J. Hunter;Steven K. Troncone
影响因子：
12.6
作者：
Atchudan, Raji;Edison, Thomas Nesakumar Jebakumar Immanuel;Lee, Yong Rok
通讯作者：
Lee, Yong Rok