Long-Term Nonmalignant Disease Mortality in Subjects Exposed to Transmissible Agents Present in Animals Used for Food.
Long-Term Nonmalignant Disease Mortality in Subjects Exposed to Transmissible Agents Present in Animals Used for Food.
复制标题
暴露于食用动物中存在的传染性病原体的受试者的长期非恶性疾病死亡率。
DOI：
10.1089/vbz.2016.1984
复制
发表时间：
2016
期刊：
影响因子：
--
通讯作者：
Johnson,EricS
中科院分区：
文献类型：
--
作者：
Ndetan,Harrison;Ekanem,UwemedimbukS;Faramawi,MohammedF;Chedjieu,IreneP;Thapa,Susan;Johnson,BiancaK;Johnson,KemmianD;Surani,SalimaS;Johnson,EricS
目的：研究大量接触食品动物及其生的或未煮熟的产品中存在的传染性病原体的受试者的非恶性疾病死亡率。方法：将屠宰和加工厂的一组肉类处理人员的死亡率与美国普通人群的死亡率进行比较。结果：观察到已知与感染相关的疾病的死亡率过高，这些疾病包括败血症、慢性肾炎、肾脏和输尿管疾病、肾病和输尿管疾病。胰腺、肝硬化、急性和亚急性心内膜炎、急性风湿热、心脏功能性疾病、主动脉瘤、颅内和棘内脓肿、脑膜炎。还观察到缺血性心脏病和糖尿病的死亡率过高，这些疾病没有确定的传染性病因，但与感染有关。结论：如果食用动物及其原材料中存在的传染源导致人类长期疾病和死亡，这项研究重要地指出了可能的疾病，其中许多已知与感染有关。观察到的缺血性心脏病和糖尿病的过高死亡率与将这些疾病与感染联系起来的现有证据是一致的，并产生了新的假设，即食用动物及其产品中存在的微生物可能在这些疾病的发生中发挥感染作用，因此需要进一步研究。
Objective:To study mortality from nonmalignant diseases in subjects with high exposure to transmissible agents present in animals used for food, and in their raw or inadequately cooked products.Methods:Mortality was compared in a cohort of meat handlers in slaughtering and processing plants with that of the U.S. general population.Results:Excess mortality was observed for conditions known to be associated with infections—these include, septicemia, chronic nephritis, diseases of the kidney and ureter, diseases of the pancreas, cirrhosis of the liver, acute and subacute endocarditis, acute rheumatic fever, functional diseases of the heart, aortic aneurysm, intracranial and intraspinous abscess, and meningitis. Excess mortality was also observed for ischemic heart disease and diabetes, conditions without an established infectious etiology, but which have been linked with infections.Conclusions:If transmissible agents present in food animals and their raw products cause long-term diseases and mortality in humans, this study importantly points to the likely diseases, many of which are already known to be associated with infections. The excess mortality observed for ischemic heart disease and diabetes is consistent with existing evidence linking these conditions with infections, and gives rise to the novel hypothesis that microbial agents present in food animals and their products may be candidates for an infective role in the occurrence of these conditions, and therefore needs further investigation.
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职业健康与安全百科全书：第三版，2 卷 日内瓦：国际劳工局，1983 年，2538 页，155.00 美元。
DOI：
--
发表时间：
1985
期刊：
影响因子：
--
作者：
C. McClure
通讯作者：
C. McClure
肉类工人的非恶性疾病死亡率：研究人畜共患传染媒介在人类非恶性慢性疾病中的作用的模型
影响因子：
4.9
作者：
Eric S. Johnson;Y. Zhou;M. Sall;M. E. Faramawi;N. Shah;A. Christopher;N. Lewis
通讯作者：
N. Lewis
螺杆菌和动脉粥样硬化。
影响因子：
4.8
作者：
J. G. Kusters;E. Kuipers
通讯作者：
E. Kuipers
影响因子：
0.9
作者：
Jeffrey L. Anderson;J. Muhlestein
通讯作者：
J. Muhlestein
DOI：
--
发表时间：
1987
期刊：
British Journal of Industrial Medicine
影响因子：
--
作者：
E. Johnson
通讯作者：
E. Johnson